Ca2+-dependent inhibition of NHE3 requires PKC alpha which binds to E3KARP to decrease surface NHE3 containing plasma membrane complexes. - Wikidata - awgldk - TriplyDB

Ca2+-dependent inhibition of NHE3 requires PKC alpha which binds to E3KARP to decrease surface NHE3 containing plasma membrane complexes.

Ca2+-dependent inhibition of NHE3 requires PKC alpha which binds to E3KARP to decrease surface NHE3 containing plasma membrane complexes.

http://www.wikidata.org/entity/Q40637935

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IRBIT, inositol 1,4,5-triphosphate (IP3) receptor-binding protein released with IP3, binds Na+/H+ exchanger NHE3 and activates NHE3 activity in response to calcium Molecular mechanisms and regulation of urinary acidification G protein-coupled receptors: what a difference a 'partner' makes Carbachol-induced MUC17 endocytosis is concomitant with NHE3 internalization and CFTR membrane recruitment in enterocytes Gastrin induces sodium-hydrogen exchanger 3 phosphorylation and mTOR activation via a phosphoinositide 3-kinase-/protein kinase C-dependent but AKT-independent pathway in renal proximal tubule cells derived from a normotensive male human.Podocytic PKC-alpha is regulated in murine and human diabetes and mediates nephrin endocytosis.The involvement of intracellular calcium in the MCT-mediated uptake of lactic acid by HeLa cells Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo.PLC-γ directly binds activated c-Src, which is necessary for carbachol-mediated inhibition of NHE3 activity in Caco-2/BBe cells Lysophosphatidic acid stimulation of NHE3 exocytosis in polarized epithelial cells occurs with release from NHERF2 via ERK-PLC-PKCδ signaling.P2Y1 receptor signaling is controlled by interaction with the PDZ scaffold NHERF-2 NHERF2/NHERF3 protein heterodimerization and macrocomplex formation are required for the inhibition of NHE3 activity by carbachol.Myosin VI mediates the movement of NHE3 down the microvillus in intestinal epithelial cells.Akt2 phosphorylates ezrin to trigger NHE3 translocation and activation Na/H exchanger regulatory factors control parathyroid hormone receptor signaling by facilitating differential activation of G(alpha) protein subunits.NHE3 mobility in brush borders increases upon NHERF2-dependent stimulation by lyophosphatidic acid.Concerted actions of NHERF2 and WNK4 in regulating TRPV5 Roles for NHERF1 and NHERF2 on the regulation of C3a receptor signaling in human mast cells The epithelial brush border Na+/H+ exchanger NHE3 associates with the actin cytoskeleton by binding to ezrin directly and via PDZ domain-containing Na+/H+ exchanger regulatory factor (NHERF) proteins.NHERF1 and NHERF2 are necessary for multiple but usually separate aspects of basal and acute regulation of NHE3 activity.Serotonin modifies cytoskeleton and brush-border membrane architecture in human intestinal epithelial cells.Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo.NHERF2 is necessary for basal activity, second messenger inhibition, and LPA stimulation of NHE3 in mouse distal ileum.Elevated calcium acutely regulates dynamic interactions of NHERF2 and NHE3 proteins in opossum kidney (OK) cell microvilli.Sorting nexin 27 regulates basal and stimulated brush border trafficking of NHE3.Evolutionary origins of eukaryotic sodium/proton exchangers.NHERF and regulation of the renal sodium-hydrogen exchanger NHE3.Restoration of Na+/H+ exchanger NHE3-containing macrocomplexes ameliorates diabetes-associated fluid loss NHERF family and NHE3 regulation.The role of NHERF-1 in the regulation of renal proximal tubule sodium-hydrogen exchanger 3 and sodium-dependent phosphate cotransporter 2a.The PDZ scaffold NHERF-2 interacts with mGluR5 and regulates receptor activity.The emerging role of PDZ adapter proteins for regulation of intestinal ion transport.Emerging roles of alkali cation/proton exchangers in organellar homeostasis.NHERF2 protein mobility rate is determined by a unique C-terminal domain that is also necessary for its regulation of NHE3 protein in OK cells.The calcineurin homologous protein-1 increases Na(+)/H(+) -exchanger 3 trafficking via ezrin phosphorylation NHE3 regulatory complexes Fine-tuning of GPCR activity by receptor-interacting proteins Regulation of electroneutral NaCl absorption by the small intestine New advances in the pathophysiology of intestinal ion transport and barrier function in diarrhea and the impact on therapy.BAX inhibitor-1 enhances cancer metastasis by altering glucose metabolism and activating the sodium-hydrogen exchanger: the alteration of mitochondrial function.

P2860

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P2860

Ca2+-dependent inhibition of NHE3 requires PKC alpha which binds to E3KARP to decrease surface NHE3 containing plasma membrane complexes.

http://www.wikidata.org/entity/Q40637935

description

2003 nî lūn-bûn

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

2003年论文

@zh

2003年论文

@zh-cn

name

Ca2+-dependent inhibition of N ...... ing plasma membrane complexes.

@en

type

label

Ca2+-dependent inhibition of N ...... ing plasma membrane complexes.

@en

prefLabel

Ca2+-dependent inhibition of N ...... ing plasma membrane complexes.

@en

P1433

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P356

AJPCELL.00017.2003

P1433

American Journal of Physiology - Cell Physiology

P1476

Ca2+-dependent inhibition of N ...... ing plasma membrane complexes.

@en

P2093

Boyoung Cha

http://www.w3.org/2001/XMLSchema#string

Darlene A Dartt

http://www.w3.org/2001/XMLSchema#string

Driss Zoukhri

http://www.w3.org/2001/XMLSchema#string

Jae Ho Kim

http://www.w3.org/2001/XMLSchema#string

Jung Woong Choi

http://www.w3.org/2001/XMLSchema#string

Kazuya Kawano

http://www.w3.org/2001/XMLSchema#string

Mark Donowitz

http://www.w3.org/2001/XMLSchema#string

Whaseon Lee-Kwon

http://www.w3.org/2001/XMLSchema#string

P2860

Calcineurin homologous protein as an essential cofactor for Na+/H+ exchangers

Ca(2+)-dependent inhibition of Na+/H+ exchanger 3 (NHE3) requires an NHE3-E3KARP-alpha-actinin-4 complex for oligomerization and endocytosis

NHE3 kinase A regulatory protein E3KARP binds the epithelial brush border Na+/H+ exchanger NHE3 and the cytoskeletal protein ezrin

A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange

cAMP-mediated inhibition of the epithelial brush border Na+/H+ exchanger, NHE3, requires an associated regulatory protein

Glucocorticoid activation of Na(+)/H(+) exchanger isoform 3 revisited. The roles of SGK1 and NHERF2

Role of phosphorylation in regulation of the assembly of endocytic coat complexes

Protein kinase C: structure, function, and regulation

Phosphorylation of dynamin I on Ser-795 by protein kinase C blocks its association with phospholipids.

Specific association of megalin and the Na+/H+ exchanger isoform NHE3 in the proximal tubule.

P304

C1527-36

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scholarly article

P356

10.1152/AJPCELL.00017.2003

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P433

6

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P478

285

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P577

2003-09-03T00:00:00Z

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P698

12954600

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