Radiation sensitization of human cancer cells in vivo by inhibiting the activity of PI3K using LY294002.
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Two-stage phase I dose-escalation study of intratumoral reovirus type 3 dearing and palliative radiotherapy in patients with advanced cancersDiscovery and SAR of Novel 2,3-Dihydroimidazo[1,2-c]quinazoline PI3K Inhibitors: Identification of Copanlisib (BAY 80-6946)Role of Akt signaling in resistance to DNA-targeted therapyTargeted therapy for advanced prostate cancer: inhibition of the PI3K/Akt/mTOR pathwayAnalysis of DNA methylation and gene expression in radiation-resistant head and neck tumorsS6K1 and 4E-BP1 are independent regulated and control cellular growth in bladder cancerCurcumin significantly enhances dual PI3K/Akt and mTOR inhibitor NVP-BEZ235-induced apoptosis in human renal carcinoma Caki cells through down-regulation of p53-dependent Bcl-2 expression and inhibition of Mcl-1 protein stabilityRadiosensitization of epidermal growth factor receptor/HER2-positive pancreatic cancer is mediated by inhibition of Akt independent of ras mutational status.Selective targeting of radiation-resistant tumor-initiating cells.A phase I study of nelfinavir concurrent with temozolomide and radiotherapy in patients with glioblastoma multiforme.Inhibition of radiation induced migration of human head and neck squamous cell carcinoma cells by blocking of EGF receptor pathways.Akt: a double-edged sword in cell proliferation and genome stability.MAPK signal-integrating kinase controls cap-independent translation and cell type-specific cytotoxicity of an oncolytic poliovirusSelective inhibition of HER2-positive breast cancer cells by the HIV protease inhibitor nelfinavir.Expression of PI3K/AKT pathway in gastric cancer and its blockade suppresses tumor growth and metastasis.ON01210.Na (Ex-RAD®) mitigates radiation damage through activation of the AKT pathway.A novel curcumin analog (H-4073) enhances the therapeutic efficacy of cisplatin treatment in head and neck cancerProtecting intestinal epithelial cell number 6 against fission neutron irradiation through NF-κB signaling pathway.Radiation Enhancement of Head and Neck Squamous Cell Carcinoma by the Dual PI3K/mTOR Inhibitor PF-05212384.The HIV protease inhibitor nelfinavir downregulates Akt phosphorylation by inhibiting proteasomal activity and inducing the unfolded protein response.Expression of phosphorylated Akt/mTOR and clinical significance in human ameloblastoma.DNA-Dependent Protein Kinase As Molecular Target for Radiosensitization of Neuroblastoma Cells.Molecular targets for potentiation of radiation-induced cell killing.The life and death of DNA-PK.Increased expression of pAKT is associated with radiation resistance in cervical cancer.Nutrient restriction and radiation therapy for cancer treatment: when less is morePreclinical pharmacokinetics and metabolism of a novel prototype DNA-PK inhibitor NU7026Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations.Safety and tolerability of AZD5363 in Japanese patients with advanced solid tumorsTargeting the PI3K-Akt pathway in kidney cancer.Beta1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts.Clinical target promiscuity: lessons from ras molecular trials.Repositioning HIV protease inhibitors as cancer therapeuticsTargeting the PI3K-AKT-mTOR signaling network in cancer.YM155 reverses cisplatin resistance in head and neck cancer by decreasing cytoplasmic survivin levels.Modulating the tumor microenvironment to increase radiation responsiveness.beta1 integrin targeting to enhance radiation therapy.Novel PI3K and mTOR Inhibitor NVP-BEZ235 Radiosensitizes Breast Cancer Cell Lines under Normoxic and Hypoxic Conditions.Expanding therapeutic targets in bladder cancer: the PI3K/Akt/mTOR pathway.Therapeutic strategies for head and neck cancer based on p53 status.
P2860
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P2860
Radiation sensitization of human cancer cells in vivo by inhibiting the activity of PI3K using LY294002.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Radiation sensitization of hum ...... tivity of PI3K using LY294002.
@en
type
label
Radiation sensitization of hum ...... tivity of PI3K using LY294002.
@en
prefLabel
Radiation sensitization of hum ...... tivity of PI3K using LY294002.
@en
P2093
P1476
Radiation sensitization of hum ...... tivity of PI3K using LY294002.
@en
P2093
Anjali K Gupta
George J Cerniglia
Mona S Ahmed
Rosemarie Mick
Ruth J Muschel
Vincent J Bakanauskas
W Gillies McKenna
P304
P356
10.1016/S0360-3016(03)00214-1
P407
P577
2003-07-01T00:00:00Z