Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis.
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LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stressInsights into Aurora-A Kinase Activation Using Unnatural Amino Acids Incorporated by Chemical ModificationChemical genetic screen for AMPKα2 substrates uncovers a network of proteins involved in mitosisAminoimidazole carboxamide ribonucleotide (AICAR) inhibits the growth of retinoblastoma in vivo by decreasing angiogenesis and inducing apoptosisMyocardial ischemia and increased heart work modulate the phosphorylation state of eukaryotic elongation factor-2Cytoplasmic signaling in the control of mitochondrial uproar?Quantitative phosphokinome analysis of the Met pathway activated by the invasin internalin B from Listeria monocytogenes.PPARbeta activation induces rapid changes of both AMPK subunit expression and AMPK activation in mouse skeletal muscle.PKA phosphorylates and inactivates AMPKalpha to promote efficient lipolysisHypercontractility of intestinal longitudinal smooth muscle induced by cytokines is mediated by the nuclear factor-κB/AMP-activated kinase/myosin light chain kinase pathway.Functional roles of VASP phosphorylation in the regulation of chemotaxis and osmotic stress responseDeficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction.Uveal melanoma cell growth is inhibited by aminoimidazole carboxamide ribonucleotide (AICAR) partially through activation of AMP-dependent kinase.Dietary energy availability affects primary and metastatic breast cancer and metformin efficacy.Retinoblastoma cells are inhibited by aminoimidazole carboxamide ribonucleotide (AICAR) partially through activation of AMP-dependent kinase.The outcome of renal ischemia-reperfusion injury is unchanged in AMPK-β1 deficient mice.Metformin and cancer.Sestrin2 modulates AMPK subunit expression and its response to ionizing radiation in breast cancer cells.β-Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK).Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancerRegulation of a truncated isoform of AMP-activated protein kinase α (AMPKα) in response to hypoxia in the muscle of Pacific oyster Crassostrea gigas.Stretch-sensitive down-regulation of the miR-144/451 cluster in vascular smooth muscle and its role in AMP-activated protein kinase signalingRegulation of AMPK by the ubiquitin proteasome systemAMPK inhibition in health and disease.Involvement of metformin and AMPK in the radioresponse and prognosis of luminal versus basal-like breast cancer treated with radiotherapyIschemia-induced stimulation of Na-K-Cl cotransport in cerebral microvascular endothelial cells involves AMP kinase.The recruitment of AMP-activated protein kinase to glycogen is regulated by autophosphorylation.Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinaseThe SNF1 Kinase Ubiquitin-associated Domain Restrains Its Activation, Activity, and the Yeast Life SpanCytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapyEpidermal growth factor-induced vacuolar (H+)-atpase assembly: a role in signaling via mTORC1 activation.Effects of adenosine monophosphate-activated kinase in the ventral horn of rabbit spinal cord after transient ischemiaOestrogen receptors interact with the α-catalytic subunit of AMP-activated protein kinase.Inhibition of vascular smooth muscle growth via signaling crosstalk between AMP-activated protein kinase and cAMP-dependent protein kinase.AMP-Activated Protein Kinase Signalling in Cancer and Cardiac Hypertrophy.Role of AMP-activated protein kinase in healthy and diseased hearts.AMP-activated protein kinase contributes to zinc-induced neuronal death via activation by LKB1 and induction of Bim in mouse cortical cultures.A plant kinase plays roles in defense response against geminivirus by phosphorylation of a viral pathogenesis protein.Differential effects of energy stress on AMPK phosphorylation and apoptosis in experimental brain tumor and normal brain
P2860
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P2860
Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Identification of phosphorylat ...... by site-directed mutagenesis.
@en
type
label
Identification of phosphorylat ...... by site-directed mutagenesis.
@en
prefLabel
Identification of phosphorylat ...... by site-directed mutagenesis.
@en
P2093
P50
P356
P1476
Identification of phosphorylat ...... by site-directed mutagenesis.
@en
P2093
Angela Woods
Jayne Bayliss
Mark H Rider
Roland Turk
P304
28434-28442
P356
10.1074/JBC.M303946200
P407
P577
2003-05-21T00:00:00Z