SUMO modification of STAT1 and its role in PIAS-mediated inhibition of gene activation.
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PIASy stimulates HIF1α SUMOylation and negatively regulates HIF1α activity in response to hypoxiaPIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73DNA methylation represses IFN-gamma-induced and signal transducer and activator of transcription 1-mediated IFN regulatory factor 8 activation in colon carcinoma cellsFunctional role of NF-IL6beta and its sumoylation and acetylation modifications in promoter activation of cyclooxygenase 2 gene.Flaviviral NS4b, chameleon and jack-in-the-box roles in viral replication and pathogenesis, and a molecular target for antiviral interventionThe 'PINIT' motif, of a newly identified conserved domain of the PIAS protein family, is essential for nuclear retention of PIAS3LA functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetesRegulation of cytokine signaling pathways by PIAS proteinsEbola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinerySUMO modification of heterogeneous nuclear ribonucleoproteinsExchange protein activated by cyclic AMP (Epac)-mediated induction of suppressor of cytokine signaling 3 (SOCS-3) in vascular endothelial cells.Differential regulation of the two transcriptional activation domains of the coiled-coil coactivator CoCoA by sumoylation.Interferon-stimulated genes: a complex web of host defenses.Structure-function analysis indicates that sumoylation modulates DNA-binding activity of STAT1.A novel proteomics approach to identify SUMOylated proteins and their modification sites in human cellsModification of the erythroid transcription factor GATA-1 by SUMO-1.Cloning the human SUMO1 promoter.PIAS3 induction of PRB sumoylation represses PRB transactivation by destabilizing its retention in the nucleusAdenovirus sequesters phosphorylated STAT1 at viral replication centers and inhibits STAT dephosphorylation.Dysregulation of janus kinases and signal transducers and activators of transcription in cancer.SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation.Signal transducer and activator of transcription (STAT) signalling and T-cell lymphomas.Multisite protein modification and intramolecular signaling.PIAS3 negatively regulates RANKL-mediated osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblasts.SUMO1 negatively regulates BRCA1-mediated transcription, via modulation of promoter occupancyIdentification of intracellular proteins and signaling pathways in human endothelial cells regulated by angiotensin-(1-7)Biology and significance of the JAK/STAT signalling pathways.Targeting the PIAS1 SUMO ligase pathway to control inflammation.Phosphorylation meets nuclear import: a review.A novel repressor domain is required for maximal growth inhibition by the IRF-1 tumor suppressor.The logic of communication: roles for mobile transcription factors in plants.Sumoylation Modulates the Susceptibility to Type 1 Diabetes.Canonical and Non-Canonical Aspects of JAK-STAT Signaling: Lessons from Interferons for Cytokine Responses.PIASx acts as an Elk-1 coactivator by facilitating derepression.The role of JAK-STAT signaling pathway and its regulators in the fate of T helper cells.Mutually exclusive STAT1 modifications identified by Ubc9/substrate dimerization-dependent SUMOylation.PRMT1-mediated arginine methylation of PIAS1 regulates STAT1 signaling.A conserved catalytic residue in the ubiquitin-conjugating enzyme family.Stat1 and SUMO modification.Modulation of the activation of Stat1 by the interferon-gamma receptor complex.
P2860
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P2860
SUMO modification of STAT1 and its role in PIAS-mediated inhibition of gene activation.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
SUMO modification of STAT1 and its role in PIAS-mediated inhibition of gene activation.
@en
type
label
SUMO modification of STAT1 and its role in PIAS-mediated inhibition of gene activation.
@en
prefLabel
SUMO modification of STAT1 and its role in PIAS-mediated inhibition of gene activation.
@en
P2860
P356
P1476
SUMO modification of STAT1 and its role in PIAS-mediated inhibition of gene activation.
@en
P2093
Curt M Horvath
Richard S Rogers
P2860
P304
30091-30097
P356
10.1074/JBC.M301344200
P407
P577
2003-05-22T00:00:00Z