The generation of killer cells to trinitrophenyl-modified allogeneic targets by lymphocyte populations negatively selected to strong alloantigens.
about
The control of specificity of cytotoxic T lymphocytes by the major histocompatibility complex (AG-B) in rats and identification of a new alloantigen system showing no AG-B restriction.The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: evidence for T helpCytotoxic T cells recognize male antigen and H-2 as distinct entities.T-cell populations specifically depleted of alloreactive potential cannot be induced to lyse H-2-different virus-infected target cellsH-2 antigens of the thymus determine lymphocyte specificity.Thymic reconstitution of nude F1 mice with one or both parental thymus grafts.Suppression of T cells specific for the nonthymic parental H-2 haplotype in thymus-grafted chimeras.Absence of H-2 restriction in primary and secondary mixed-lymphocyte reactions to strong M1s determinantsCytotoxic T lymphocyte responses by chimeric thymocytes. Self-recognition is determined early in T cell development.Responder T cells depleted of alloreactive cells react to antigen presented on allogeneic macrophages from nonresponder strains.Induction of neonatal tolerance to H-2k in B6 mice does not allow the emergence of T cells specific for H-2k plus vaccinia virus.H-2 restriction as a consequence of intentional priming: T cells of fully allogeneic chimeric mice as well as of normal mice respond to foreign antigens in the context of H-2 determinants not encountered on thymic epithelial cellsRole of H-2 gene products in the function of T helper cells from normal and chimeric mice in vivo.Thymus and lymphohemopoietic cells: their role in T cell maturation in selection of T cells' H-2-restriction-specificity and in H-2 linked Ir gene control.HLA-D region molecules restrict proliferative T cell responses to antigen.Ia antigens as restriction molecules in Ir-gene controlled T-cell proliferation.Impact of thymus on the generation of immunocompetence and diversity of antigen-specific MHC-restricted cytotoxic T-lymphocyte precursors.Fact and speculation on the function of immune response genes in antigen presentation.T-T cell interactions during cytotoxic T lymphocyte (CTL) responses: T cell derived helper factor (Interleukin 2) as a probe to analyze CTL responsiveness and thymic maturation of CTL progenitors.Cytotoxic T cells learn specificity for self H-2 during differentiation in the thymus.T cells specific for hapten-modified self are precommitted for self major histocompatibility complex antigens before encounter with the hapten.Vaccinia-specific cytotoxic T-cell responses in the context of H-2 antigens not encountered in thymus may reflect aberrant recognition of a virus-H-2 complex.T-helper function of parent leads to F1 chimeras. Presence of a separate T-cell subgroup able to stimulate allogeneic B cells but not syngeneic B cells.Positive selection of immature alpha beta T cells.The collaborative phenotype of secondary B cells is determined by T lymphocytes during in vivo immunization.H-2 restriction as a consequence of intentional priming. Frequency analysis of alloantigen-restricted, trinitrophenyl-specific cytotoxic T lymphocyte precursors within thymocytes of normal mice.Allorestricted cytotoxic T cells. Large numbers of allo-H-2Kb-restricted antihapten and antiviral cytotoxic T cell populations clonally develop in vitro from murine splenic precursor T cells.
P2860
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P2860
The generation of killer cells to trinitrophenyl-modified allogeneic targets by lymphocyte populations negatively selected to strong alloantigens.
description
1977 nî lūn-bûn
@nan
1977年の論文
@ja
1977年論文
@yue
1977年論文
@zh-hant
1977年論文
@zh-hk
1977年論文
@zh-mo
1977年論文
@zh-tw
1977年论文
@wuu
1977年论文
@zh
1977年论文
@zh-cn
name
The generation of killer cells ...... lected to strong alloantigens.
@en
type
label
The generation of killer cells ...... lected to strong alloantigens.
@en
prefLabel
The generation of killer cells ...... lected to strong alloantigens.
@en
P2093
P2860
P356
P1476
The generation of killer cells ...... lected to strong alloantigens.
@en
P2093
P2860
P304
P356
10.1084/JEM.146.2.361
P407
P577
1977-08-01T00:00:00Z