PKM2 and the tricky balance of growth and energy in cancer.
about
Metabolic reprogramming as a novel regulator of skeletal muscle development and regenerationPKM2: the thread linking energy metabolism reprogramming with epigenetics in cancerProtein-tyrosine phosphatase 1B substrates and metabolic regulationSpecial nutrition in mouse developmental oocytes.SAICAR stimulates pyruvate kinase isoform M2 and promotes cancer cell survival in glucose-limited conditionsM2 isoform of pyruvate kinase is dispensable for tumor maintenance and growth.Protein tyrosine phosphatase 1B regulates pyruvate kinase M2 tyrosine phosphorylationThe long and winding road to the mitochondrial pyruvate carrierA metabolic link to skeletal muscle wasting and regeneration.Phosphoglycerate dehydrogenase is dispensable for breast tumor maintenance and growth.Integrating autophagy and metabolism in cancer.PKM2 Promotes Cell Survival and Invasion Under Metabolic Stress by Enhancing Warburg Effect in Pancreatic Ductal Adenocarcinoma.Regulatory circuit of PKM2/NF-κB/miR-148a/152-modulated tumor angiogenesis and cancer progression.Overexpression of pyruvate kinase M2 predicts a poor prognosis for patients with osteosarcoma.RGD-modified oncolytic adenovirus-harboring shPKM2 exhibits a potent cytotoxic effect in pancreatic cancer via autophagy inhibition and apoptosis promotion.Succinyl-5-aminoimidazole-4-carboxamide-1-ribose 5'-Phosphate (SAICAR) Activates Pyruvate Kinase Isoform M2 (PKM2) in Its Dimeric Form.PKM2, a Central Point of Regulation in Cancer Metabolism.Lapachol inhibits glycolysis in cancer cells by targeting pyruvate kinase M2.Arginine Deprivation Inhibits the Warburg Effect and Upregulates Glutamine Anaplerosis and Serine Biosynthesis in ASS1-Deficient Cancers.Isoform-specific deletion of PKM2 constrains tumor initiation in a mouse model of soft tissue sarcoma.High PKM2 expression is independently correlated with decreased overall survival in hepatocellular carcinoma
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P2860
PKM2 and the tricky balance of growth and energy in cancer.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
PKM2 and the tricky balance of growth and energy in cancer.
@en
type
label
PKM2 and the tricky balance of growth and energy in cancer.
@en
prefLabel
PKM2 and the tricky balance of growth and energy in cancer.
@en
P2860
P1433
P1476
PKM2 and the tricky balance of growth and energy in cancer.
@en
P2093
Jeffrey C Rathmell
P2860
P304
P356
10.1016/J.MOLCEL.2011.06.003
P577
2011-06-01T00:00:00Z