Evidence for an alternative glycolytic pathway in rapidly proliferating cells. - Wikidata - awgldk - TriplyDB

Evidence for an alternative glycolytic pathway in rapidly proliferating cells.

Evidence for an alternative glycolytic pathway in rapidly proliferating cells.

http://www.wikidata.org/entity/Q34535762

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Pyruvate dehydrogenase kinase as a novel therapeutic target in oncology Warburg effect and translocation-induced genomic instability: two yeast models for cancer cells ZBTB2 increases PDK4 expression by transcriptional repression of RelA/p65 Applications of metabolomics in cancer research Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis Stable isotope-resolved metabolomics and applications for drug development Mitochondria in Cancer Energy Metabolism: Culprits or Bystanders?The sweet trap in tumors: aerobic glycolysis and potential targets for therapy Energy metabolism in neurodevelopment and medulloblastoma Interplay Between Metabolism and Oncogenic Process: Role of microRNAs Targeting amino acid metabolism in cancer growth and anti-tumor immune response 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling Pyruvate kinase: Function, regulation and role in cancer Autophagy in stem cells.Application of metabolomics in drug resistant breast cancer research Bioinformatics and systems biology Pyruvate kinase M2 at a glance Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis Serine is a natural ligand and allosteric activator of pyruvate kinase M2 Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation Heterogeneity of glycolysis in cancers and therapeutic opportunities.ROS homeostasis and metabolism: a critical liaison for cancer therapy Infection homeostasis: implications for therapeutic and immune programming of metabolism in controlling infection Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) is a pro-survival, endoplasmic reticulum (ER) stress response gene involved in tumor cell adaptation to nutrient availability Identification of metabolites in the normal ovary and their transformation in primary and metastatic ovarian cancer Bioactivity-guided identification and cell signaling technology to delineate the lactate dehydrogenase A inhibition effects of Spatholobus suberectus on breast cancer Metabolic dysfunction and altered mitochondrial dynamics in the utrophin-dystrophin deficient mouse model of duchenne muscular dystrophy Variations in Glycogen Synthesis in Human Pluripotent Stem Cells with Altered Pluripotent States Assessment of FBA Based Gene Essentiality Analysis in Cancer with a Fast Context-Specific Network Reconstruction Method The space of enzyme regulation in HeLa cells can be inferred from its intracellular metabolome Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer Metabolic reprogramming: a cancer hallmark even warburg did not anticipate Proteomic screening method for phosphopeptide motif binding proteins using peptide libraries.A metabolic perturbation by U0126 identifies a role for glutamine in resveratrol-induced cell death.Role of Increased n-acetylaspartate Levels in Cancer.Integrating gene and protein expression data with genome-scale metabolic networks to infer functional pathways Analysis and interpretation of transcriptomic data obtained from extended Warburg effect genes in patients with clear cell renal cell carcinoma.Towards Real-time Metabolic Profiling of Cancer with Hyperpolarized Succinate Stress-induced cleavage of Myc promotes cancer cell survival

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P2860

Evidence for an alternative glycolytic pathway in rapidly proliferating cells.

http://www.wikidata.org/entity/Q34535762

description

2010 nî lūn-bûn

@nan

2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Evidence for an alternative glycolytic pathway in rapidly proliferating cells.

@ast

Evidence for an alternative glycolytic pathway in rapidly proliferating cells.

@en

Evidence for an alternative glycolytic pathway in rapidly proliferating cells.

@nl

type

label

Evidence for an alternative glycolytic pathway in rapidly proliferating cells.

@ast

Evidence for an alternative glycolytic pathway in rapidly proliferating cells.

@en

Evidence for an alternative glycolytic pathway in rapidly proliferating cells.

@nl

prefLabel

Evidence for an alternative glycolytic pathway in rapidly proliferating cells.

@ast

Evidence for an alternative glycolytic pathway in rapidly proliferating cells.

@en

Evidence for an alternative glycolytic pathway in rapidly proliferating cells.

@nl

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SCIENCE.1188015

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Evidence for an alternative glycolytic pathway in rapidly proliferating cells.

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P2093

Daniel Amador-Noguez

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Gerhard Wagner

http://www.w3.org/2001/XMLSchema#string

Greg J Heffron

http://www.w3.org/2001/XMLSchema#string

Hadar Sharfi

http://www.w3.org/2001/XMLSchema#string

John M Asara

http://www.w3.org/2001/XMLSchema#string

Joshua D Rabinowitz

http://www.w3.org/2001/XMLSchema#string

Kenneth D Swanson

http://www.w3.org/2001/XMLSchema#string

Matthew G Vander Heiden

http://www.w3.org/2001/XMLSchema#string

P2860

HMDB: the Human Metabolome Database

Dephosphorylation of 2,3-bisphosphoglycerate by MIPP expands the regulatory capacity of the Rapoport-Luebering glycolytic shunt

Understanding the Warburg effect: the metabolic requirements of cell proliferation

Pyruvate kinase M2 is a phosphotyrosine-binding protein

Probability-based protein identification by searching sequence databases using mass spectrometry data

An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database

Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis

Pyruvate kinase type M2 and its role in tumor growth and spreading

Glycolytic enzymes can modulate cellular life span

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

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scholarly article

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10.1126/SCIENCE.1188015

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5998

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329

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Heather R Christofk

Lewis C. Cantley

Jason W. Locasale

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2010-09-01T00:00:00Z

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46288437

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20847263

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3030121

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