Effects of troglitazone on HepG2 viability and mitochondrial function. - Wikidata - awgldk - TriplyDB

Effects of troglitazone on HepG2 viability and mitochondrial function.

Effects of troglitazone on HepG2 viability and mitochondrial function.

http://www.wikidata.org/entity/Q40705895

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Evidence-based selection of training compounds for use in the mechanism-based integrated prediction of drug-induced liver injury in man The Importance of Patient-Specific Factors for Hepatic Drug Response and Toxicity Idiosyncratic drug-induced liver injury and the role of inflammatory stress with an emphasis on an animal model of trovafloxacin hepatotoxicity Troglitazone induces cytotoxicity in part by promoting the degradation of peroxisome proliferator-activated receptor γ co-activator-1α protein.Profiling of the Tox21 chemical collection for mitochondrial function to identify compounds that acutely decrease mitochondrial membrane potential.Idiosyncratic drug hepatotoxicity.The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR).Drug-induced mitochondrial toxicity.Tissue engineering and organ structure: a vascularized approach to liver and lung.Integrative toxicoproteomics implicates impaired mitochondrial glutathione import as an off-target effect of troglitazone Inflammatory stress and idiosyncratic hepatotoxicity: hints from animal models.Troglitazone, but not rosiglitazone, damages mitochondrial DNA and induces mitochondrial dysfunction and cell death in human hepatocytes.Transcriptional, Functional, and Mechanistic Comparisons of Stem Cell-Derived Hepatocytes, HepaRG Cells, and Three-Dimensional Human Hepatocyte Spheroids as Predictive In Vitro Systems for Drug-Induced Liver Injury.A systematic assessment of mitochondrial function identified novel signatures for drug-induced mitochondrial disruption in cells.The mitochondrial superoxide/thioredoxin-2/Ask1 signaling pathway is critically involved in troglitazone-induced cell injury to human hepatocytes.Adverse effects of anti-tuberculosis drugs on HepG2 cell bioenergetics.Cytotoxicity of thiazolidinedione-, oxazolidinedione- and pyrrolidinedione-ring containing compounds in HepG2 cells.Study of the Effects of ATP Suppliers and Thiol Reductants on Toxicity of Pioglitazone in Isolated Rat Liver Mitochondria.Mitochondrial dysfunction induced by sertraline, an antidepressant agent.Mitochondrial toxicity assessment in industry--a decade of technology development and insight.Sensitivity of liver injury in heterozygous Sod2 knockout mice treated with troglitazone or acetaminophen.In vitro effect of N-acetylcysteine on hepatocyte injury caused by dichlorodiphenyltrichloroethane and its metabolites.

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P2860

Effects of troglitazone on HepG2 viability and mitochondrial function.

http://www.wikidata.org/entity/Q40705895

description

2002 nî lūn-bûn

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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2002年论文

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2002年论文

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name

Effects of troglitazone on HepG2 viability and mitochondrial function.

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type

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Effects of troglitazone on HepG2 viability and mitochondrial function.

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prefLabel

Effects of troglitazone on HepG2 viability and mitochondrial function.

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Toxicological Sciences

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Effects of troglitazone on HepG2 viability and mitochondrial function.

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P2093

Beverly E Maleeff

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Catherine X Hu

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Edit Kurali

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Heath C Thomas

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Lester W Schwartz

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Mark A Tirmenstein

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Padma K Narayanan

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Timothy K Hart

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Tracy L Gales

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131-138

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scholarly article

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10.1093/TOXSCI/69.1.131

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1

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69

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2002-09-01T00:00:00Z

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11172910

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12215667

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