Effects of troglitazone on HepG2 viability and mitochondrial function.
about
Evidence-based selection of training compounds for use in the mechanism-based integrated prediction of drug-induced liver injury in manThe Importance of Patient-Specific Factors for Hepatic Drug Response and ToxicityIdiosyncratic drug-induced liver injury and the role of inflammatory stress with an emphasis on an animal model of trovafloxacin hepatotoxicityTroglitazone induces cytotoxicity in part by promoting the degradation of peroxisome proliferator-activated receptor γ co-activator-1α protein.Profiling of the Tox21 chemical collection for mitochondrial function to identify compounds that acutely decrease mitochondrial membrane potential.Idiosyncratic drug hepatotoxicity.The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR).Drug-induced mitochondrial toxicity.Tissue engineering and organ structure: a vascularized approach to liver and lung.Integrative toxicoproteomics implicates impaired mitochondrial glutathione import as an off-target effect of troglitazoneInflammatory stress and idiosyncratic hepatotoxicity: hints from animal models.Troglitazone, but not rosiglitazone, damages mitochondrial DNA and induces mitochondrial dysfunction and cell death in human hepatocytes.Transcriptional, Functional, and Mechanistic Comparisons of Stem Cell-Derived Hepatocytes, HepaRG Cells, and Three-Dimensional Human Hepatocyte Spheroids as Predictive In Vitro Systems for Drug-Induced Liver Injury.A systematic assessment of mitochondrial function identified novel signatures for drug-induced mitochondrial disruption in cells.The mitochondrial superoxide/thioredoxin-2/Ask1 signaling pathway is critically involved in troglitazone-induced cell injury to human hepatocytes.Adverse effects of anti-tuberculosis drugs on HepG2 cell bioenergetics.Cytotoxicity of thiazolidinedione-, oxazolidinedione- and pyrrolidinedione-ring containing compounds in HepG2 cells.Study of the Effects of ATP Suppliers and Thiol Reductants on Toxicity of Pioglitazone in Isolated Rat Liver Mitochondria.Mitochondrial dysfunction induced by sertraline, an antidepressant agent.Mitochondrial toxicity assessment in industry--a decade of technology development and insight.Sensitivity of liver injury in heterozygous Sod2 knockout mice treated with troglitazone or acetaminophen.In vitro effect of N-acetylcysteine on hepatocyte injury caused by dichlorodiphenyltrichloroethane and its metabolites.
P2860
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P2860
Effects of troglitazone on HepG2 viability and mitochondrial function.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Effects of troglitazone on HepG2 viability and mitochondrial function.
@en
type
label
Effects of troglitazone on HepG2 viability and mitochondrial function.
@en
prefLabel
Effects of troglitazone on HepG2 viability and mitochondrial function.
@en
P2093
P356
P1476
Effects of troglitazone on HepG2 viability and mitochondrial function.
@en
P2093
Beverly E Maleeff
Catherine X Hu
Edit Kurali
Heath C Thomas
Lester W Schwartz
Mark A Tirmenstein
Padma K Narayanan
Timothy K Hart
Tracy L Gales
P304
P356
10.1093/TOXSCI/69.1.131
P577
2002-09-01T00:00:00Z