Human blood platelet adhesion to artery subendothelium is mediated by factor VIII-Von Willebrand factor bound to the subendothelium.
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Evidence that the primary binding site of von Willebrand factor that mediates platelet adhesion on subendothelium is not collagenInitial glycosylation and acidic pH in the Golgi apparatus are required for multimerization of von Willebrand factorInteractions of thrombospondin with extracellular matrix proteins: selective binding to type V collagenImmunolocalization of von Willebrand protein in Weibel-Palade bodies of human endothelial cells150-kD von Willebrand factor binding protein extracted from human vascular subendothelium is type VI collagenMicrofluidics and coagulation biologyFactoring in Factor VIII With Acute Ischemic StrokePrimary arrest of circulating platelets on collagen involves phosphorylation of Syk, cortactin and focal adhesion kinase: studies under flow conditionsCav3.1 (alpha1G) controls von Willebrand factor secretion in rat pulmonary microvascular endothelial cells.Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogenADAP is required for normal alphaIIbbeta3 activation by VWF/GP Ib-IX-V and other agonists.Activation-independent platelet adhesion and aggregation under elevated shear stressThe cytoplasmic domain of the platelet glycoprotein Ibalpha is phosphorylated at serine 609.Effects of increased von Willebrand factor levels on primary hemostasis in thrombocytopenic patients with liver cirrhosisDifferentiation of patients with subtype IIb-like von Willebrand's disease by means of perfusion experiments with reconstituted blood.Properties of human asialo-factor VIII. A ristocetin-independent platelet-aggregating agent.Clinical pathology and hemostatic abnormalities in experimental African horsesickness.Humanized mouse model of thrombosis is predictive of the clinical efficacy of antiplatelet agents.Mediation of fibrin-induced release of von Willebrand factor from cultured endothelial cells by the fibrin beta chainvon Willebrand factor synthesized by endothelial cells from a patient with type IIB von Willebrand disease supports platelet adhesion normally but has an increased affinity for platelets.Functional self-association of von Willebrand factor during platelet adhesion under flow.Expression of the phenotypic abnormality of platelet-type von Willebrand disease in a recombinant glycoprotein Ib alpha fragment.Platelet adhesion receptors: novel targets for anti-thrombotic therapy.Von Willebrand's disease: a clinical and molecular enigma. Twelfth Annual Paul M. Aggeler Memorial Lecture.Selectin-like kinetics and biomechanics promote rapid platelet adhesion in flow: the GPIb(alpha)-vWF tether bond.Mechanics of transient platelet adhesion to von Willebrand factor under flowArginine-glycine-aspartic acid- and fibrinogen gamma-chain carboxyterminal peptides inhibit platelet adherence to arterial subendothelium at high wall shear rates. An effect dissociable from interference with adhesive protein binding.In vivo analysis of the role of O-glycosylations of von Willebrand factor.Mapping the N-glycome of human von Willebrand factor.Markers for the lymphatic endothelium: in search of the holy grail?Structural basis of von Willebrand factor binding to platelet glycoprotein Ib and collagen. Effects of disulfide reduction and limited proteolysis of polymeric von Willebrand factor.Binding and covalent cross-linking of purified von Willebrand factor to native monomeric collagen.von Willebrand protein facilitates platelet incorporation in polymerizing fibrinBiosynthesis of von Willebrand protein by human megakaryocytes.Fibrin induces release of von Willebrand factor from endothelial cells.Fibrinogen-independent platelet adhesion and thrombus formation on subendothelium mediated by glycoprotein IIb-IIIa complex at high shear rate.Evaluation of prothrombin time and activated partial thromboplastin time in hypertensive patients attending a tertiary hospital in calabar, NigeriaFunctional domains on von Willebrand factor. Recognition of discrete tryptic fragments by monoclonal antibodies that inhibit interaction of von Willebrand factor with platelets and with collagen.Platelet interaction with rabbit subendothelium in von Willebrand's disease: altered thrombus formation distinct from defective platelet adhesionEndothelial cell synthesis of von Willebrand antigen II, von Willebrand factor, and von Willebrand factor/von Willebrand antigen II complex.
P2860
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P2860
Human blood platelet adhesion to artery subendothelium is mediated by factor VIII-Von Willebrand factor bound to the subendothelium.
description
1979 nî lūn-bûn
@nan
1979年の論文
@ja
1979年論文
@yue
1979年論文
@zh-hant
1979年論文
@zh-hk
1979年論文
@zh-mo
1979年論文
@zh-tw
1979年论文
@wuu
1979年论文
@zh
1979年论文
@zh-cn
name
Human blood platelet adhesion ...... r bound to the subendothelium.
@en
type
label
Human blood platelet adhesion ...... r bound to the subendothelium.
@en
prefLabel
Human blood platelet adhesion ...... r bound to the subendothelium.
@en
P2093
P2860
P356
P1433
P1476
Human blood platelet adhesion ...... r bound to the subendothelium.
@en
P2093
Bolhuis PA
Sakariassen KS
P2860
P2888
P304
P356
10.1038/279636A0
P407
P577
1979-06-01T00:00:00Z
P6179
1027563950