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Dioxin-induced CYP1A1 transcription in vivo: the aromatic hydrocarbon receptor mediates transactivation, enhancer-promoter communication, and changes in chromatin structureToxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlifeResponses of genes involved in cell cycle control to diverse DNA damaging chemicals in human lung adenocarcinoma A549 cells.Exocrine pancreatic pathology in female Harlan Sprague-Dawley rats after chronic treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin and dioxin-like compoundsCloning and characterization of HuR, a ubiquitously expressed Elav-like proteinA direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycleIdentification of functional domains of the aryl hydrocarbon receptorA novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxinA novel 4 S [3H]beta-naphthoflavone-binding protein in liver cytosol of female Sprague-Dawley rats treated with aryl hydrocarbon receptor agonistsDioxin induces localized, graded changes in chromatin structure: implications for Cyp1A1 gene transcriptionAryl hydrocarbon receptor imported into the nucleus following ligand binding is rapidly degraded via the cytosplasmic proteasome following nuclear exportMolecular mechanism of inhibition of estrogen-induced cathepsin D gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in MCF-7 cellsInduction of cytochrome P4501A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin or indolo(3,2-b)carbazole is associated with oxidative DNA damageAnimal models of human response to dioxinsExpression and subcellular localization of the aryl hydrocarbon receptor nuclear translocator (ARNT) protein in mouse and chicken over developmental timeGene-Environment Interactions Target Mitogen-activated Protein 3 Kinase 1 (MAP3K1) Signaling in Eyelid MorphogenesisDifferential regulation of polysome mRNA levels in mouse Hepa-1C1C7 cells exposed to dioxinA modified QuEChERS approach for the screening of dioxins and furans in sediments.Analysis of epoxyeicosatrienoic acids by chiral liquid chromatography/electron capture atmospheric pressure chemical ionization mass spectrometry using [13C]-analog internal standards.Aryl hydrocarbon receptor (AHR)-regulated transcriptomic changes in rats sensitive or resistant to major dioxin toxicities.Human risk assessment and TEFs.Dioxin exposure and porcine reproductive hormonal activity.Reactivity parameters in structure-activity relationship-based risk assessment of chemicals.Implications for risk assessment of suggested nongenotoxic mechanisms of chemical carcinogenesis.Hazard and risk assessment of chemical mixtures using the toxic equivalency factor approach.Methoxychlor reduces estradiol levels by altering steroidogenesis and metabolism in mouse antral follicles in vitro.Combined 17β-Estradiol with TCDD Promotes M2 Polarization of Macrophages in the Endometriotic Milieu with Aid of the Interaction between Endometrial Stromal Cells and Macrophages.Very low-dose (femtomolar) 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) disrupts steroidogenic enzyme mRNAs and steroid secretion by human luteinizing granulosa cells.Polychlorinated biphenyl congeners that increase the glucuronidation and biliary excretion of thyroxine are distinct from the congeners that enhance the serum disappearance of thyroxineAryl hydrocarbon receptor-deficient mice develop heightened inflammatory responses to cigarette smoke and endotoxin associated with rapid loss of the nuclear factor-kappaB component RelB.Inherent and benzo[a]pyrene-induced differential aryl hydrocarbon receptor signaling greatly affects life span, atherosclerosis, cardiac gene expression, and body and heart growth in miceSrc-mediated aryl hydrocarbon and epidermal growth factor receptor cross talk stimulates colon cancer cell proliferationEffect of transient expression of the oestrogen receptor on constitutive and inducible CYP1A1 in Hs578T human breast cancer cellsThe aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cell cycle and differentiated state independently of dioxinTransactivation domains facilitate promoter occupancy for the dioxin-inducible CYP1A1 gene in vivo.The challenge of predicting drug toxicity in silico.Hepatic transcriptional networks induced by exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.Down-regulation of major histocompatibility complex Q1b gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin.The aryl hydrocarbon receptor as a target for estrogen receptor-negative breast cancer chemotherapyThe aryl hydrocarbon receptor (AhR) in the regulation of cell-cell contact and tumor growth.
P2860
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P2860
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Mechanistic aspects of dioxin action.
@en
type
label
Mechanistic aspects of dioxin action.
@en
prefLabel
Mechanistic aspects of dioxin action.
@en
P356
P1476
Mechanistic aspects of dioxin action.
@en
P2093
Whitlock JP Jr
P304
P356
10.1021/TX00036A003
P577
1993-11-01T00:00:00Z