Mutations in conserved regions 1, 2, and 3 of Raf-1 that activate transforming activity.

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CRAF R391W is a melanoma driver oncogene Integrating Functional Analysis in the Next-Generation Sequencing Diagnostic Pipeline of RASopathies.

P2860

Q36980239-38A72728-5335-4FFF-BC34-1F62787083EB Q49530901-38EA4424-0979-44E0-AC83-4D3AFB059886

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Mutations in conserved regions 1, 2, and 3 of Raf-1 that activate transforming activity.

Item

http://www.wikidata.org/entity/Q40740284

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2002 nî lūn-bûn

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2002年の論文

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2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

2002年论文

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name

Mutations in conserved regions 1, 2, and 3 of Raf-1 that activate transforming activity.

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type

Item

label

Mutations in conserved regions 1, 2, and 3 of Raf-1 that activate transforming activity.

@en

prefLabel

Mutations in conserved regions 1, 2, and 3 of Raf-1 that activate transforming activity.

@en

P1476

Mutations in conserved regions 1, 2, and 3 of Raf-1 that activate transforming activity.

@en

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Drell A Bottorff

http://www.w3.org/2001/XMLSchema#string

Edmond Y W Chan

http://www.w3.org/2001/XMLSchema#string

James C Stone

http://www.w3.org/2001/XMLSchema#string

Stacey L Stang

http://www.w3.org/2001/XMLSchema#string

P2860

Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

14-3-3 is not essential for Raf-1 function: identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent manner

Bcl-2 targets the protein kinase Raf-1 to mitochondria

Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine

The RafC1 cysteine-rich domain contains multiple distinct regulatory epitopes which control Ras-dependent Raf activation

S338 phosphorylation of Raf-1 is independent of phosphatidylinositol 3-kinase and Pak3

Mechanism of suppression of the Raf/MEK/extracellular signal-regulated kinase pathway by the raf kinase inhibitor protein

Purification of a murine protein-tyrosine/threonine kinase that phosphorylates and activates the Erk-1 gene product: relationship to the fission yeast byr1 gene product

The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site

Interaction of activated Ras with Raf-1 alone may be sufficient for transformation of rat2 cells

P304

189-197

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P31

scholarly article

P356

10.1002/MC.10031

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2002-04-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

11933072

http://www.w3.org/2001/XMLSchema#string

Mutations in conserved regions 1, 2, and 3 of Raf-1 that activate transforming activity.

about

P2860

P2860

Mutations in conserved regions 1, 2, and 3 of Raf-1 that activate transforming activity.

description

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type

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prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698