Identification of essential genes in cultured mammalian cells using small interfering RNAs.
about
Cloning of a novel signaling molecule, AMSH-2, that potentiates transforming growth factor beta signalingA novel role for the nuclear membrane protein emerin in association of the centrosome to the outer nuclear membraneThe entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosisThe human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosomeVinculin regulates cell-surface E-cadherin expression by binding to beta-cateninThe inner nuclear membrane protein emerin regulates beta-catenin activity by restricting its accumulation in the nucleusM phase phosphoprotein 1 is a human plus-end-directed kinesin-related protein required for cytokinesisFunctional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1Direct interaction with nup153 mediates binding of Tpr to the periphery of the nuclear pore complexCentromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome lossHuman centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathwayInhibition of macroautophagy triggers apoptosisDissecting the role of Rho-mediated signaling in contractile ring formation.Vertebrate Nup53 interacts with the nuclear lamina and is required for the assembly of a Nup93-containing complexLamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelopeThe mammalian septin MSF localizes with microtubules and is required for completion of cytokinesisThe aryl hydrocarbon receptor mediates degradation of estrogen receptor alpha through activation of proteasomesGene silencing of CENP-E by small interfering RNA in HeLa cells leads to missegregation of chromosomes after a mitotic delayEssential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formationLamin B1 is required for mouse development and nuclear integrityDepletion of a single nucleoporin, Nup107, prevents the assembly of a subset of nucleoporins into the nuclear pore complexNovel kelch-like protein, KLEIP, is involved in actin assembly at cell-cell contact sites of Madin-Darby canine kidney cellsCNV and nervous system diseases--what's new?Overlapping antisense transcription in the human genomeNup358 integrates nuclear envelope breakdown with kinetochore assemblyNuclear pore protein gp210 is essential for viability in HeLa cells and Caenorhabditis elegansRNAi-mediated depletion of the 15 KH domain protein, vigilin, induces death of dividing and non-dividing human cells but does not initially inhibit protein synthesisRibozyme-mediated REV1 inhibition reduces the frequency of UV-induced mutations in the human HPRT geneBax inhibitor-1 is overexpressed in prostate cancer and its specific down-regulation by RNA interference leads to cell death in human prostate carcinoma cellsAltered protein dynamics of disease-associated lamin A mutantsTowards in vivo application of RNA interference - new toys, old problemsExpression and localization of nuclear proteins in autosomal-dominant Emery-Dreifuss muscular dystrophy with LMNA R377H mutationProfilin is required for viral morphogenesis, syncytium formation, and cell-specific stress fiber induction by respiratory syncytial virusConserved and specific functions of mammalian ssu72Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectorsIdentification of genes involved in Ca2+ ionophore A23187-mediated apoptosis and demonstration of a high susceptibility for transcriptional repression of cell cycle genes in B lymphoblasts from a patient with Scott syndromeTelomerase inhibition by siRNA causes senescence and apoptosis in Barrett's adenocarcinoma cells: mechanism and therapeutic potential.Predicting Essential Genes and Proteins Based on Machine Learning and Network Topological Features: A Comprehensive ReviewChromatin states and nuclear organization in development--a view from the nuclear laminasiRNAs generated by recombinant human Dicer induce specific and significant but target site-independent gene silencing in human cells
P2860
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P2860
Identification of essential genes in cultured mammalian cells using small interfering RNAs.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Identification of essential ge ...... using small interfering RNAs.
@en
type
label
Identification of essential ge ...... using small interfering RNAs.
@en
prefLabel
Identification of essential ge ...... using small interfering RNAs.
@en
P2093
P1476
Identification of essential ge ...... s using small interfering RNAs
@en
P2093
P304
P407
P577
2001-12-01T00:00:00Z