Chemical synthesis and translesion replication of a cis-syn cyclobutane thymine-uracil dimer.
about
Transcription-dependent cytosine deamination is a novel mechanism in ultraviolet light-induced mutagenesis.Biological properties of single chemical-DNA adducts: a twenty year perspectiveDetrimental effects of UV-B radiation in a xeroderma pigmentosum-variant cell lineChronic low-dose ultraviolet-induced mutagenesis in nucleotide excision repair-deficient cellsUV-B radiation induces epithelial tumors in mice lacking DNA polymerase eta and mesenchymal tumors in mice deficient for DNA polymerase iotaChemical synthesis of oligonucleotides containing damaged bases for biological studies.Recruitment of DNA polymerase eta by FANCD2 in the early response to DNA damage.A cyclobutane thymine-N4-methylcytosine dimer is resistant to hydrolysis but strongly blocks DNA synthesis.Transcription-coupled repair and apoptosis provide specific protection against transcription-associated mutagenesis by ultraviolet light.Acceleration of 5-methylcytosine deamination in cyclobutane dimers by G and its implications for UV-induced C-to-T mutation hotspots.Photosensitized [2 + 2] cycloaddition of N-acetylated cytosine affords stereoselective formation of cyclobutane pyrimidine dimerReduced efficiency and increased mutagenicity of translesion DNA synthesis across a TT cyclobutane pyrimidine dimer, but not a TT 6-4 photoproduct, in human cells lacking DNA polymerase eta.
P2860
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P2860
Chemical synthesis and translesion replication of a cis-syn cyclobutane thymine-uracil dimer.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年學術文章
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name
Chemical synthesis and transle ...... lobutane thymine-uracil dimer.
@en
type
label
Chemical synthesis and transle ...... lobutane thymine-uracil dimer.
@en
prefLabel
Chemical synthesis and transle ...... lobutane thymine-uracil dimer.
@en
P2093
P2860
P356
P1476
Chemical synthesis and transle ...... lobutane thymine-uracil dimer.
@en
P2093
Chikahide Masutani
Fumio Hanaoka
Kohei Takasawa
Shigenori Iwai
P2860
P304
P356
10.1093/NAR/GKH342
P577
2004-03-12T00:00:00Z