Cytokine-mediated induction of the human elafin gene in pulmonary epithelial cells is regulated by nuclear factor-kappaB.
about
WFDC2 (HE4): a potential role in the innate immunity of the oral cavity and respiratory tract and the development of adenocarcinomas of the lungEvolution of trappin genes in mammalsIdentification of novel functional sequence variants in the gene for peptidase inhibitor 3.Overexpression of elafin in ovarian carcinoma is driven by genomic gains and activation of the nuclear factor kappaB pathway and is associated with poor overall survival.Glucocorticoid-induced reversal of interleukin-1β-stimulated inflammatory gene expression in human oviductal cells.Functional characterization of polymorphisms in the peptidase inhibitor 3 (elafin) gene and validation of their contribution to risk of acute respiratory distress syndrome.The putative ovarian tumour marker gene HE4 (WFDC2), is expressed in normal tissues and undergoes complex alternative splicing to yield multiple protein isoforms.Neutrophil elastase inhibitors as treatment for COPD.Elafin is downregulated during breast and ovarian tumorigenesis but its residual expression predicts recurrence.A functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation.Functional study of elafin cleaved by Pseudomonas aeruginosa metalloproteinases.Human rElafin Inhibits HIV-1 Replication in Its Natural Target Cells.Elafin, an elastase-specific inhibitor, is cleaved by its cognate enzyme neutrophil elastase in sputum from individuals with cystic fibrosisPulmonary epithelium, cigarette smoke, and chronic obstructive pulmonary disease.Genetic polymorphisms of peptidase inhibitor 3 (elafin) are associated with acute respiratory distress syndrome.Secretory leukocyte protease inhibitor and elafin/trappin-2: versatile mucosal antimicrobials and regulators of immunity.WAP domain proteins as modulators of mucosal immunity.Trappin-2/Elafin: a novel innate anti-human immunodeficiency virus-1 molecule of the human female reproductive tract.Inflammatory response and barrier properties of a new alveolar type 1-like cell line (TT1).Antiproteases as therapeutics to target inflammation in cystic fibrosis.Human pre-elafin inhibits a Pseudomonas aeruginosa-secreted peptidase and prevents its proliferation in complex media.Secretory component is cleaved by neutrophil serine proteinases but its epithelial production is increased by neutrophils through NF-kappa B- and p38 mitogen-activated protein kinase-dependent mechanisms.Gene expression analysis of the acute phase response using a canine microarray.Microarray analysis of differentially expressed genes in vaginal tissues from women with stress urinary incontinence compared with asymptomatic women.Elafin prevents lipopolysaccharide-induced AP-1 and NF-kappaB activation via an effect on the ubiquitin-proteasome pathway.Cervical Expression of Elafin and SLPI in Pregnancy and Their Association With Preterm Labor.
P2860
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P2860
Cytokine-mediated induction of the human elafin gene in pulmonary epithelial cells is regulated by nuclear factor-kappaB.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Cytokine-mediated induction of ...... ated by nuclear factor-kappaB.
@en
type
label
Cytokine-mediated induction of ...... ated by nuclear factor-kappaB.
@en
prefLabel
Cytokine-mediated induction of ...... ated by nuclear factor-kappaB.
@en
P2093
P2860
P356
P1476
Cytokine-mediated induction of ...... ated by nuclear factor-kappaB.
@en
P2093
P2860
P356
10.1165/AJRCMB.25.1.4341
P577
2001-07-01T00:00:00Z