The cytoplasmic and transmembrane domains of the p75 and Trk A receptors regulate high affinity binding to nerve growth factor.
about
Repression of SHP-1 expression by p53 leads to trkA tyrosine phosphorylation and suppression of breast cancer cell proliferationBrain-derived neurotrophic factorBrain-derived neurotrophic factor: role in depression and suicideNeurotrophin-regulated signalling pathwaysThe involvement of BDNF, NGF and GDNF in aging and Alzheimer's diseaseMolecular and Structural Insight into proNGF Engagement of p75NTR and SortilinIdentification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor-ligand complexNeurotrophins and the immune systemHigh-resolution fractionation of signaling endosomes containing different receptorsNRH2 is a trafficking switch to regulate sortilin localization and permit proneurotrophin-induced cell deathCharacterization of symmetric complexes of nerve growth factor and the ectodomain of the pan-neurotrophin receptor, p75NTRActivation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimersCardiovascular actions of neurotrophinsMechanisms of activation of receptor tyrosine kinases: monomers or dimers.Brain-derived neurotrophic factor and the development of structural neuronal connectivity.Understanding proneurotrophin actions: Recent advances and challenges.NGF causes TrkA to specifically attract microtubules to lipid rafts.p75NTR, but not proNGF, is upregulated following status epilepticus in mice.Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease.Does the p75 neurotrophin receptor mediate Abeta-induced toxicity in Alzheimer's disease?Dual role for p75(NTR) signaling in survival and cell death: can intracellular mediators provide an explanation?Ligand-induced dynamics of neurotrophin receptors investigated by single-molecule imaging approaches.Connecting the dots: trafficking of neurotrophins, lectins and diverse pathogens by binding to the neurotrophin receptor p75NTR.Regulation of neuronal survival and death by extracellular signals during development.Heterodimerization of p45-p75 modulates p75 signaling: structural basis and mechanism of action.NGF in Early Embryogenesis, Differentiation, and Pathology in the Nervous and Immune Systems.Brain-derived neurotrophic factor-estrogen interactions in the hippocampal mossy fiber pathway: implications for normal brain function and disease.An intracellular domain fragment of the p75 neurotrophin receptor (p75(NTR)) enhances tropomyosin receptor kinase A (TrkA) receptor functionMetalloproteases and gamma-secretase: new membrane partners regulating p75 neurotrophin receptor signaling?Brain-derived neurotrophic factor and suicide pathogenesis.Molecular kinetics of nerve growth factor receptor trafficking and activationCharacterization of NGF, trkA (NGFR) , and p75 (NTR) in Retina of Mice Lacking Reelin Glycoprotein.Neurotrophin signalling: novel insights into mechanisms and pathophysiology.Nerve growth factor modulates the tumor cells migration in ovarian cancer through the WNT/β-catenin pathway.The role of neurotrophic factors in autism.Proteolytic processing of the p75 neurotrophin receptor: A prerequisite for signalling?: Neuronal life, growth and death signalling are crucially regulated by intra-membrane proteolysis and trafficking of p75(NTR).The hippocampus, neurotrophic factors and depression: possible implications for the pharmacotherapy of depression.Tropomyosin-receptor-kinases signaling in the nervous system.Molecular mechanisms of cognitive impairment in iron deficiency: alterations in brain-derived neurotrophic factor and insulin-like growth factor expression and function in the central nervous system.Signaling molecules and transcription factors involved in the development of the sympathetic nervous system, with special emphasis on the superior cervical ganglion.
P2860
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P2860
The cytoplasmic and transmembrane domains of the p75 and Trk A receptors regulate high affinity binding to nerve growth factor.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
The cytoplasmic and transmembr ...... inding to nerve growth factor.
@en
type
label
The cytoplasmic and transmembr ...... inding to nerve growth factor.
@en
prefLabel
The cytoplasmic and transmembr ...... inding to nerve growth factor.
@en
P2093
P2860
P356
P1476
The cytoplasmic and transmembr ...... binding to nerve growth factor
@en
P2093
Esposito D
Hempstead BL
Stephens RM
P2860
P304
32687-32695
P356
10.1074/JBC.M011674200
P407
P577
2001-07-02T00:00:00Z