Somatic mutations of WNT/wingless signaling pathway components in primitive neuroectodermal tumors. - Wikidata - awgldk - TriplyDB

Somatic mutations of WNT/wingless signaling pathway components in primitive neuroectodermal tumors.

Somatic mutations of WNT/wingless signaling pathway components in primitive neuroectodermal tumors.

http://www.wikidata.org/entity/Q40795419

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Functional characterization of WNT7A signaling in PC12 cells: interaction with A FZD5 x LRP6 receptor complex and modulation by Dickkopf proteins Biological background of pediatric medulloblastoma and ependymoma: a review from a translational research perspective Expression of stabilized beta-catenin in differentiated neurons of transgenic mice does not result in tumor formation.Fenretinide (4-HPR) Targets Caspase-9, ERK 1/2 and the Wnt3a/β-Catenin Pathway in Medulloblastoma Cells and Medulloblastoma Cell Spheroids Functional and molecular interactions between the HGF/c-Met pathway and c-Myc in large-cell medulloblastoma.Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features.Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort.Potential therapeutic implications of cancer stem cells in glioblastoma Anti-tumor mechanisms of valproate: a novel role for an old drug.Nuclear accumulation of beta-catenin protein indicates activation of wnt signaling in chemically induced rat nephroblastomas Neural development and the ontogeny of central nervous system tumors.Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation.Classifying the medulloblastoma: insights from morphology and molecular genetics.Downregulation of Wnt2 and beta-catenin by siRNA suppresses malignant glioma cell growth.The Wnt signaling pathway in bipolar disorder.WNT3 inhibits cerebellar granule neuron progenitor proliferation and medulloblastoma formation via MAPK activation.Brain tumours: classification and genes Dickkopf-1 is an epigenetically silenced candidate tumor suppressor gene in medulloblastoma Early recurrence in standard-risk medulloblastoma patients with the common idic(17)(p11.2) rearrangement An interferon response gene expression signature is activated in a subset of medulloblastomas Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups.Targeting stem cells in brain tumors.Clinical neuropathology practice guide 3-2013: levels of evidence and clinical utility of prognostic and predictive candidate brain tumor biomarkers Signaling pathway and molecular subgroups of medulloblastoma.An investigation of WNT pathway activation and association with survival in central nervous system primitive neuroectodermal tumours (CNS PNET).Update on the integrated histopathological and genetic classification of medulloblastoma - a practical diagnostic guideline.The potential impact of tumour biology on improved clinical practice for medulloblastoma: progress towards biologically driven clinical trials.Wnt signaling in development and disease The perivascular niche microenvironment in brain tumor progression.Molecular diagnostics of CNS embryonal tumors.Cancer stem cells in glioblastoma--molecular signaling and therapeutic targeting.Review: personalized mice: modelling the molecular heterogeneity of medulloblastoma.The way Wnt works: components and mechanism.Glioma stem cells: turpis omen in nomen? (The evil in the name?).Medulloblastoma: recurrence and metastasis.Inhibition of WNT signaling attenuates self-renewal of SHH-subgroup medulloblastoma.Genomic Alterations of Adamantinomatous and Papillary Craniopharyngioma.Molecular stratification of medulloblastoma: comparison of histological and genetic methods to detect Wnt activated tumours.Exploration of Involved Key Genes and Signaling Diversity in Brain Tumors.Medulloblastoma: experimental models and reality.

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Somatic mutations of WNT/wingless signaling pathway components in primitive neuroectodermal tumors.

http://www.wikidata.org/entity/Q40795419

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International Journal of Cancer

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Somatic mutations of WNT/wingl ...... mitive neuroectodermal tumors.

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A Koch

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A Waha

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F Berthold

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G Reifenberger

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N Sörensen

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P2860

Identification of c-MYC as a target of the APC pathway

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

A common human skin tumour is caused by activating mutations in beta-catenin

Somatic mutation of the APC gene in gastric cancer: frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma

Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein

Stabilization of beta-catenin by genetic defects in melanoma cell lines

Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathways.

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