Defect of histone acetyltransferase activity of the nuclear transcriptional coactivator CBP in Rubinstein-Taybi syndrome.
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Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcriptionBinding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylationThe metastasis-associated proteins 1 and 2 form distinct protein complexes with histone deacetylase activityRubinstein-Taybi Syndrome: spectrum of CREBBP mutations in Italian patients.Minireview: the SRC family of coactivators: an entrée to understanding a subset of polygenic diseases?Catalytic mechanism of histone acetyltransferase p300: from the proton transfer to acetylation reactionThe new field of epigenomics: implications for cancer and other common disease research.Epigenetics and assisted reproductive technology: a call for investigation.Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause diseaseTranscription coactivators p300 and CBP are necessary for photoreceptor-specific chromatin organization and gene expression.Characterization of 14 novel deletions underlying Rubinstein-Taybi syndrome: an update of the CREBBP deletion repertoire.Acetylation of nucleosomal histones by p300 facilitates transcription from tax-responsive human T-cell leukemia virus type 1 chromatin templatePolyisoprenylated benzophenone, garcinol, a natural histone acetyltransferase inhibitor, represses chromatin transcription and alters global gene expression.Crebinostat: a novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity.Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription.CREB binding protein functions during successive stages of eye development in Drosophila.A genetic screen identifies putative targets and binding partners of CREB-binding protein in the developing Drosophila eye.The role of genetics in the establishment and maintenance of the epigenome.Histone deacetylase inhibitors: from target to clinical trials.Whole exome sequencing for a patient with Rubinstein-Taybi syndrome reveals de novo variants besides an overt CREBBP mutation.Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implicationsAnti-Cancer Effect of 3-(4-dimethylamino phenyl)-N-hydroxy-2-propenamide in MCF-7 Human Breast CancerIs histone acetylation the most important physiological function for CBP and p300?Joining the dots: from chromatin remodeling to neuronal plasticityRole of histone acetylation in the control of gene expression.Expression of HDAC1 and CBP/p300 in human colorectal carcinomasDevelopment of neurodevelopmental disorders: a regulatory mechanism involving bromodomain-containing proteinsThe therapeutic uses of chromatin-modifying agents.The Rubinstein-Taybi syndrome: modeling mental impairment in the mouse.Inhibition of histone acetyltransferase by glycosaminoglycansDecoding the epigenetic language of neuronal plasticity.Chemical biology of histone acetyltransferase natural compounds modulators.Analysis of mutations within the intron20 splice donor site of CREBBP in patients with and without classical RSTS.Constitutional Epi/Genetic Conditions: Genetic, Epigenetic, and Environmental Factors.Chemical and structural biology of protein lysine deacetylasesThe PHD type zinc finger is an integral part of the CBP acetyltransferase domain.From Whole Gene Deletion to Point Mutations of EP300-Positive Rubinstein-Taybi Patients: New Insights into the Mutational Spectrum and Peculiar Clinical Hallmarks.Analysis of histone deacetylase inhibitor, depsipeptide (FR901228), effect on multiple myeloma.Insights into genotype-phenotype correlations from CREBBP point mutation screening in a cohort of 46 Rubinstein-Taybi syndrome patients.Huntington's disease. Exploiting expression.
P2860
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P2860
Defect of histone acetyltransferase activity of the nuclear transcriptional coactivator CBP in Rubinstein-Taybi syndrome.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Defect of histone acetyltransf ...... in Rubinstein-Taybi syndrome.
@en
type
label
Defect of histone acetyltransf ...... in Rubinstein-Taybi syndrome.
@en
prefLabel
Defect of histone acetyltransf ...... in Rubinstein-Taybi syndrome.
@en
P2093
P356
P1476
Defect of histone acetyltransf ...... in Rubinstein-Taybi syndrome.
@en
P2093
M G Rosenfeld
M Yanagisawa
R Kurokawa
P304
P356
10.1093/HMG/10.10.1071
P577
2001-05-01T00:00:00Z