A totally synthetic polyoxime malaria vaccine containing Plasmodium falciparum B cell and universal T cell epitopes elicits immune responses in volunteers of diverse HLA types.
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Vaccines for preventing malaria (pre-erythrocytic)WITHDRAWN: Vaccines for preventing malaria.Vaccines for preventing malariaDelivery of host cell-directed therapeutics for intracellular pathogen clearanceRapid Determination of HLA B*07 Ligands from the West Nile Virus NY99 GenomeAdenovirus 5-vectored P. falciparum vaccine expressing CSP and AMA1. Part A: safety and immunogenicity in seronegative adultsImmune Adjuvant Effect of Molecularly-defined Toll-Like Receptor LigandsImaging effector functions of human cytotoxic CD4+ T cells specific for Plasmodium falciparum circumsporozoite protein.Multivalency - a way to enhance binding avidities and bioactivity - preliminary applications to EPO.Phase I trial of an alhydrogel adjuvanted hepatitis B core virus-like particle containing epitopes of Plasmodium falciparum circumsporozoite protein.Why functional pre-erythrocytic and bloodstage malaria vaccines fail: a meta-analysis of fully protective immunizations and novel immunological model.Chelation of Ca²⁺ ions by a peptide from the repeat region of the Plasmodium falciparum circumsporozoite protein.An unstable Th epitope of P. falciparum fosters central memory T cells and anti-CS antibody responses.Plasmodium vivax promiscuous T-helper epitopes defined and evaluated as linear peptide chimera immunogens.Th-cytotoxic T-lymphocyte chimeric epitopes extended by Nepsilon-palmitoyl lysines induce herpes simplex virus type 1-specific effector CD8+ Tc1 responses and protect against ocular infection.A modified hepatitis B virus core particle containing multiple epitopes of the Plasmodium falciparum circumsporozoite protein provides a highly immunogenic malaria vaccine in preclinical analyses in rodent and primate hostsTLR-based immune adjuvants.Improved method for predicting linear B-cell epitopes.Plasmodium falciparum variability and immune evasion proceed from antigenicity of consensus sequences from DBL6ε; generalization to all DBL from VAR2CSA.A DNA prime-modified vaccinia virus ankara boost vaccine encoding thrombospondin-related adhesion protein but not circumsporozoite protein partially protects healthy malaria-naive adults against Plasmodium falciparum sporozoite challenge.Measuring naturally acquired immune responses to candidate malaria vaccine antigens in Ghanaian adults.A candidate dual vaccine against influenza and noroviruses.Self-assembled peptide nanofibers raising durable antibody responses against a malaria epitope.Peptide dendrimers.Priming of CD4+ T cells and development of CD4+ T cell memory; lessons for malaria.Plasmodium falciparum synthetic LbL microparticle vaccine elicits protective neutralizing antibody and parasite-specific cellular immune responses.HLA-DR: molecular insights and vaccine design.Enhanced immunogenicity of Plasmodium falciparum peptide vaccines using a topical adjuvant containing a potent synthetic Toll-like receptor 7 agonist, imiquimodCellular effector mechanisms against Plasmodium liver stages.Dendrimers and miktoarm polymers based multivalent nanocarriers for efficient and targeted drug delivery.Peptide-Decorated Dendrimers and Their Bioapplications.Dendrimer-based nanocarriers: a versatile platform for drug delivery.Epitope mapping of Brugia malayi ALT-2 and the development of a multi-epitope vaccine for lymphatic filariasis.Phase I testing of a malaria vaccine composed of hepatitis B virus core particles expressing Plasmodium falciparum circumsporozoite epitopes.Intranasal administration of a synthetic lipopeptide without adjuvant induces systemic immune responses.A linear peptide containing minimal T- and B-cell epitopes of Plasmodium falciparum circumsporozoite protein elicits protection against transgenic sporozoite challenge.Safety and enhanced immunogenicity of a hepatitis B core particle Plasmodium falciparum malaria vaccine formulated in adjuvant Montanide ISA 720 in a phase I trialPrediction and identification of B cell epitopes derived from EWS/FLI-l fusion protein of Ewing's sarcoma.Lipopeptide epitopes extended by an Nepsilon-palmitoyl-lysine moiety increase uptake and maturation of dendritic cells through a Toll-like receptor-2 pathway and trigger a Th1-dependent protective immunity.Solid phase oxime ligations for the iterative synthesis of polypeptide conjugates.
P2860
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P2860
A totally synthetic polyoxime malaria vaccine containing Plasmodium falciparum B cell and universal T cell epitopes elicits immune responses in volunteers of diverse HLA types.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
A totally synthetic polyoxime ...... lunteers of diverse HLA types.
@en
type
label
A totally synthetic polyoxime ...... lunteers of diverse HLA types.
@en
prefLabel
A totally synthetic polyoxime ...... lunteers of diverse HLA types.
@en
P2093
P1476
A totally synthetic polyoxime ...... lunteers of diverse HLA types.
@en
P2093
Calvo-Calle JM
Hochstrasser D
Oliveira GA
Schneider M
P304
P356
10.4049/JIMMUNOL.166.1.481
P407
P577
2001-01-01T00:00:00Z