Ordering of ceramide formation, caspase activation, and mitochondrial changes during CD95- and DNA damage-induced apoptosis.
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A house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell deathApoptosis and signalling in acid sphingomyelinase deficient cellsInhibition of acid sphingomyelinase by tricyclic antidepressants and analogonsTemporal relationships between ceramide production, caspase activation and mitochondrial dysfunction in cell lines with varying sensitivity to anti-Fas-induced apoptosisCD40L induces multidrug resistance to apoptosis in breast carcinoma and lymphoma cells through caspase independent and dependent pathwaysCadmium-induced ceramide formation triggers calpain-dependent apoptosis in cultured kidney proximal tubule cells.Identification of Mg2+ -dependent neutral sphingomyelinase 1 as a mediator of heat stress-induced ceramide generation and apoptosis.A novel mitochondrial sphingomyelinase in zebrafish cells.Does ceramide play a role in neural cell apoptosis?Glucosylceramide synthase does not attenuate the ceramide pool accumulating during apoptosis induced by CD95 or anti-cancer regimens.Ceramide response post-photodamage is absent after treatment with HA14-1Interdiction of sphingolipid metabolism to improve standard cancer therapies.Cell death in the peripheral nervous system: potential rescue strategies.Protein kinase Cdelta amplifies ceramide formation via mitochondrial signaling in prostate cancer cells.Ceramide synthase-dependent ceramide generation and programmed cell death: involvement of salvage pathway in regulating postmitochondrial events.New advances on structural and biological functions of ceramide in apoptotic/necrotic cell death and cancer.Ceramide: second messenger or modulator of membrane structure and dynamics?Ceramide accumulation precedes caspase-3 activation during apoptosis of A549 human lung adenocarcinoma cellsRadiation induced cytochrome c release causes loss of rat colonic fluid absorption by damage to crypts and pericryptal myofibroblastsMitochondrial ceramide and the induction of apoptosisSphingomyelin hydrolysis to ceramide during the execution phase of apoptosis results from phospholipid scrambling and alters cell-surface morphology.DNA damage induces down-regulation of UDP-glucose ceramide glucosyltransferase, increases ceramide levels and triggers apoptosis in p53-deficient cancer cells.Irradiation leads to apoptosis of Kupffer cells by a Hsp27-dependant pathway followed by release of TNF-alpha.Anti-apoptotic Bcl-2 Family Proteins Disassemble Ceramide ChannelsC-6 Ceramide Induces p53 Dependent Apoptosis in Human Astrocytoma Grade4 (Glioblastoma Multiforme) Cells.Recombinant mistletoe lectin induces p53-independent apoptosis in tumour cells and cooperates with ionising radiation.A chicken-or-egg conundrum in apoptosis: which comes first? Ceramide or PKCdelta?Reduction of radiation-induced apoptosis by specific expression of Bcl-2 in normal cells.Bcl-2 rescues ceramide- and etoposide-induced mitochondrial apoptosis through blockage of caspase-2 activation.Selective induction of apoptosis in MCF7 cancer-cell by targeted liposomes functionalised with mannose-6-phosphate.Requirement for aspartate-cleaved bid in apoptosis signaling by DNA-damaging anti-cancer regimens.Overcoming resistance to gamma-rays in squamous carcinoma cells by poly-drug elevation of ceramide levels.Ceramide and glutathione define two independently regulated pathways of cell death initiated by p53 in Molt-4 leukaemia cells.Perillyl alcohol as a radio-/chemosensitizer in malignant glioma.Role of ceramide in mediating apoptosis of irradiated LNCaP prostate cancer cells.The acid sphingomyelinase inhibitor SR33557 counteracts TNF-alpha-mediated potentiation of IL-1beta-induced NF-kappaB activation in the insulin-producing cell line Rinm5F.Ceramide induces cell death in the human prostatic carcinoma cell lines PC3 and DU145 but does not seem to be involved in Fas-mediated apoptosis.Uncoupling ceramide glycosylation by transfection of glucosylceramide synthase antisense reverses adriamycin resistance.Apoptosis and sphingomyelin hydrolysis. The flip side.Long-chain ceramide is a potent inhibitor of the mitochondrial permeability transition pore.
P2860
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P2860
Ordering of ceramide formation, caspase activation, and mitochondrial changes during CD95- and DNA damage-induced apoptosis.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Ordering of ceramide formation ...... DNA damage-induced apoptosis.
@en
type
label
Ordering of ceramide formation ...... DNA damage-induced apoptosis.
@en
prefLabel
Ordering of ceramide formation ...... DNA damage-induced apoptosis.
@en
P2093
P2860
P356
P1476
Ordering of ceramide formation ...... DNA damage-induced apoptosis.
@en
P2093
A D Tepper
E de Vries
W J van Blitterswijk
P2860
P304
P356
10.1172/JCI5457
P407
P577
1999-04-01T00:00:00Z