Ceramide accumulation precedes caspase-3 activation during apoptosis of A549 human lung adenocarcinoma cells
about
Neutral sphingomyelinase 2 (nSMase2) is a phosphoprotein regulated by calcineurin (PP2B)Ceramide-induced apoptosis in renal tubular cells: a role of mitochondria and sphingosine-1-phoshateSphingolipids as cell fate regulators in lung development and diseaseChronic LPS inhalation causes emphysema-like changes in mouse lung that are associated with apoptosisAblation of dihydroceramide desaturase confers resistance to etoposide-induced apoptosis in vitroVam3, a resveratrol dimer, inhibits cigarette smoke-induced cell apoptosis in lungs by improving mitochondrial function.Loss of stearoyl-CoA desaturase 1 rescues cardiac function in obese leptin-deficient mice.Dietary and behavioral interventions protect against age related activation of caspase cascades in the canine brain.Lung injury and cancer: Mechanistic insights into ceramide and EGFR signaling under cigarette smoke.Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice.Lung injury and lung cancer caused by cigarette smoke-induced oxidative stress: Molecular mechanisms and therapeutic opportunities involving the ceramide-generating machinery and epidermal growth factor receptor.nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosis.Neutral sphingomyelinase 2: a novel target in cigarette smoke-induced apoptosis and lung injury.Lung cancer and lung injury: the dual role of ceramidePeripheral neuropathy in the Twitcher mouse involves the activation of axonal caspase 3.Neutral sphingomyelinase 2 activity and protein stability are modulated by phosphorylation of five conserved serines.Src regulates cigarette smoke-induced ceramide generation via neutral sphingomyelinase 2 in the airway epitheliumSuperoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramideShort-term magnesium deficiency upregulates sphingomyelin synthase and p53 in cardiovascular tissues and cells: relevance to the de novo synthesis of ceramide.Neutral sphingomyelinase 2 is activated by cigarette smoke to augment ceramide-induced apoptosis in lung cell death.Streptococcus pneumoniae-induced caspase 6-dependent apoptosis in lung epithelium.Sphingolipids in the DNA damage response.Targeting sphingosine-1-phosphate signaling in lung diseases.Ceramide induces apoptosis in human lung adenocarcinoma A549 cells through mitogen-activated protein kinases.Poly(ADP-ribose)polymerase activation mediates lung epithelial cell death in vitro but is not essential in hyperoxia-induced lung injury.EBNA3C-mediated regulation of aurora kinase B contributes to Epstein-Barr virus-induced B-cell proliferation through modulation of the activities of the retinoblastoma protein and apoptotic caspasesShort-term magnesium deficiency results in decreased levels of serum sphingomyelin, lipid peroxidation, and apoptosis in cardiovascular tissues.Dihydroceramide-desaturase-1-mediated caspase 9 activation through ceramide plays a pivotal role in palmitic acid-induced HepG2 cell apoptosis.Ceramide species are elevated in human breast cancer and are associated with less aggressiveness.LC-MS based sphingolipidomic study on A549 human lung adenocarcinoma cell line and its taxol-resistant strain
P2860
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P2860
Ceramide accumulation precedes caspase-3 activation during apoptosis of A549 human lung adenocarcinoma cells
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Ceramide accumulation precedes ...... uman lung adenocarcinoma cells
@ast
Ceramide accumulation precedes ...... uman lung adenocarcinoma cells
@en
type
label
Ceramide accumulation precedes ...... uman lung adenocarcinoma cells
@ast
Ceramide accumulation precedes ...... uman lung adenocarcinoma cells
@en
prefLabel
Ceramide accumulation precedes ...... uman lung adenocarcinoma cells
@ast
Ceramide accumulation precedes ...... uman lung adenocarcinoma cells
@en
P2093
P2860
P1476
Ceramide accumulation precedes ...... uman lung adenocarcinoma cells
@en
P2093
Adili Tsaba
Edward A Medina
Reuven Rasooly
Tommer Ravid
Tzipora Goldkorn
P2860
P304
P356
10.1152/AJPLUNG.00172.2002
P577
2003-02-07T00:00:00Z