PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding.
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A key commitment step in erythropoiesis is synchronized with the cell cycle clock through mutual inhibition between PU.1 and S-phase progressionThe transcriptional repressor GFI-1 antagonizes PU.1 activity through protein-protein interactionFunctional cross-antagonism between transcription factors FLI-1 and EKLFJun blockade of erythropoiesis: role for repression of GATA-1 by HERP2.Systematic RNAi studies on the role of Sp/KLF factors in globin gene expression and erythroid differentiationGATA-1 and Gfi-1B interplay to regulate Bcl-xL transcriptionMultistable and multistep dynamics in neutrophil differentiation.Zinc finger proteins in cancer progressionSimilarities between the Epstein-Barr Virus (EBV) Nuclear Protein EBNA1 and the Pioneer Transcription Factor FoxA: Is EBNA1 a "Bookmarking" Oncoprotein that Alters the Host Cell Epigenotype?Transcription factor-mediated reprogramming toward hematopoietic stem cellsThe Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous ProteinsBromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genesA general model for binary cell fate decision gene circuits with degeneracy: indeterminacy and switch behavior in the absence of cooperativityDirect binding of pRb/E2F-2 to GATA-1 regulates maturation and terminal cell division during erythropoiesisPotential autoregulation of transcription factor PU.1 by an upstream regulatory elementSki can negatively regulates macrophage differentiation through its interaction with PU.1.GATA1 function, a paradigm for transcription factors in hematopoiesisWIPI-dependent autophagy during neutrophil differentiation of NB4 acute promyelocytic leukemia cells.Multiple ETS family proteins regulate PF4 gene expression by binding to the same ETS binding site.PU.1 and Haematopoietic Cell Fate: Dosage MattersGfi-1 regulates the erythroid transcription factor network through Id2 repression in murine hematopoietic progenitor cells.Antagonistic effect of CCAAT enhancer-binding protein-alpha and Pax5 in myeloid or lymphoid lineage choice in common lymphoid progenitorsOrigin, development, and homeostasis of tissue-resident macrophages.Genome-Scale CRISPR-Mediated Control of Gene Repression and ActivationProtein-protein interaction between Fli-1 and GATA-1 mediates synergistic expression of megakaryocyte-specific genes through cooperative DNA binding.The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages.Erythroblast transformation by the friend spleen focus-forming virus is associated with a block in erythropoietin-induced STAT1 phosphorylation and DNA binding and correlates with high expression of the hematopoietic phosphatase SHP-1.Gene expression fluctuations in murine hematopoietic stem cells with cell cycle progression.GATA-1-mediated proliferation arrest during erythroid maturation.B-Lymphoma cells with epigenetic silencing of Pax5 trans-differentiate into macrophages, but not other hematopoietic lineages.C/EBPalpha directs monocytic commitment of primary myeloid progenitors.Early mammalian erythropoiesis requires the Dot1L methyltransferaseLocal chromatin dynamics of transcription factors imply cell-lineage specific functions during cellular differentiation.PU.1 and pRB interact and cooperate to repress GATA-1 and block erythroid differentiationActivation of the Flt3 signal transduction cascade rescues and enhances type I interferon-producing and dendritic cell development.The interplay between the master transcription factor PU.1 and miR-424 regulates human monocyte/macrophage differentiation.Spi-1/PU.1 activates transcription through clustered DNA occupancy in erythroleukemiaC/EBPalpha binds and activates the PU.1 distal enhancer to induce monocyte lineage commitment.Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors.Important genes in the pathogenesis of 5q- syndrome and their connection with ribosomal stress and the innate immune system pathway.
P2860
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P2860
PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
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2000年學術文章
@zh-hant
name
PU.1 inhibits GATA-1 function ...... y blocking GATA-1 DNA binding.
@en
type
label
PU.1 inhibits GATA-1 function ...... y blocking GATA-1 DNA binding.
@en
prefLabel
PU.1 inhibits GATA-1 function ...... y blocking GATA-1 DNA binding.
@en
P2093
P1433
P1476
PU.1 inhibits GATA-1 function ...... y blocking GATA-1 DNA binding.
@en
P2093
Mueller BU
Narravula S
Torbett BE
P304
P407
P577
2000-10-01T00:00:00Z