Growth factor-dependent activation of the Ras-Raf-MEK-MAPK pathway in the human pancreatic carcinoma cell line PANC-1 carrying activated K-ras: implications for cell proliferation and cell migration.
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Sperm-associated antigen 1 is expressed early in pancreatic tumorigenesis and promotes motility of cancer cellsPhosphatome profiling reveals PTPN2, PTPRJ and PTEN as potent negative regulators of PKB/Akt activation in Ras-mutated cancer cellsEFEMP1 binds the EGF receptor and activates MAPK and Akt pathways in pancreatic carcinoma cellsGRB2 couples RhoU to epidermal growth factor receptor signaling and cell migration.Transcriptional regulation of the Alström syndrome gene ALMS1 by members of the RFX family and Sp1DPEP1 inhibits tumor cell invasiveness, enhances chemosensitivity and predicts clinical outcome in pancreatic ductal adenocarcinomaPRAK interacts with DJ-1 and prevents oxidative stress-induced cell death.Epithelial-mesenchymal transition stimulates human cancer cells to extend microtubule-based invasive protrusions and suppresses cell growth in collagen gel.RGS16, a novel p53 and pRb cross-talk candidate inhibits migration and invasion of pancreatic cancer cells.MiR-376c down-regulation accelerates EGF-dependent migration by targeting GRB2 in the HuCCT1 human intrahepatic cholangiocarcinoma cell lineGrowth regulation via insulin-like growth factor binding protein-4 and -2 in association with mutant K-ras in lung epithelia.Oncogenic Ras in tumour progression and metastasis.Alterations in metastatic properties of hepatocellular carcinoma cell following H-ras oncogene transfectionERK2-regulated TIMP1 induces hyperproliferation of K-Ras(G12D)-transformed pancreatic ductal cells.Ras proteins: paradigms for compartmentalised and isoform-specific signalling.miR-217 regulates tumor growth and apoptosis by targeting the MAPK signaling pathway in colorectal cancer.Breast cancer biomarker measurements and standards.K-ras gene mutation enhances motility of immortalized airway cells and lung adenocarcinoma cells via Akt activation: possible contribution to non-invasive expansion of lung adenocarcinoma.Expression of MTA1 promotes motility and invasiveness of PANC-1 pancreatic carcinoma cells.Development of an assay to measure mutagenic non-homologous end-joining repair activity in mammalian cells.Targeting RET to induce medullary thyroid cancer cell apoptosis: an antagonistic interplay between PI3K/Akt and p38MAPK/caspase-8 pathways.Diverging gain-of-function mechanisms of two novel KRAS mutations associated with Noonan and cardio-facio-cutaneous syndromes.Insulin-like growth factor binding protein-5 influences pancreatic cancer cell growthRas isoform abundance and signalling in human cancer cell lines.Detection of N-RAS and K-RAS in their active GTP-bound form in acute myeloid leukemia without activating RAS mutations.Dominant negative MEKK1 inhibits survival of pancreatic cancer cells.TGFbeta1 represses proliferation of pancreatic carcinoma cells which correlates with Smad4-independent inhibition of ERK activation.Analysis of K-Ras Interactions by Biotin Ligase Tagging.Glutamine up-regulates MAPK phosphatase-1 induction via activation of Ca2+→ ERK cascade pathway.Hepatocyte growth factor/c-met signaling in regulating urokinase plasminogen activator in human stomach cancer: A potential therapeutic target for human stomach cancer.Calpain activity is generally elevated during transformation but has oncogene-specific biological functionsProtein tyrosine kinase pathway-derived ROS/NO productions contribute to G2/M cell cycle arrest in evodiamine-treated human cervix carcinoma HeLa cells.Enhancement of anchorage-independent growth of human pancreatic carcinoma MIA PaCa-2 cells by signaling from protein kinase C to mitogen-activated protein kinase.Protein kinase C nu/protein kinase D3 nuclear localization, catalytic activation, and intracellular redistribution in response to G protein-coupled receptor agonists.HOX genes regulate Rac1 activity in hematopoietic cells through control of Vav2 expression.Analysis of pathway mutation profiles highlights collaboration between cancer-associated superpathways.KRAS mutant allele-specific expression knockdown in pancreatic cancer model with systemically delivered bi-shRNA KRAS lipoplex.
P2860
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P2860
Growth factor-dependent activation of the Ras-Raf-MEK-MAPK pathway in the human pancreatic carcinoma cell line PANC-1 carrying activated K-ras: implications for cell proliferation and cell migration.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Growth factor-dependent activa ...... liferation and cell migration.
@en
type
label
Growth factor-dependent activa ...... liferation and cell migration.
@en
prefLabel
Growth factor-dependent activa ...... liferation and cell migration.
@en
P2093
P2860
P356
P1433
P1476
Growth factor-dependent activa ...... liferation and cell migration.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1203612
P407
P577
2000-06-01T00:00:00Z
P5875
P6179
1037942737