rho family GTPase activating proteins p190, bcr and rhoGAP show distinct specificities in vitro and in vivo
about
A novel Rho GTPase-activating-protein interacts with Gem, a member of the Ras superfamily of GTPasesAS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domainGrit, a GTPase-activating protein for the Rho family, regulates neurite extension through association with the TrkA receptor and N-Shc and CrkL/Crk adapter moleculesFunctional synergy between Rab5 effector Rabaptin-5 and exchange factor Rabex-5 when physically associated in a complexBPGAP1 interacts with cortactin and facilitates its translocation to cell periphery for enhanced cell migrationAn SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinasep190RhoGAP is cell cycle regulated and affects cytokinesis.Role of p120 Ras-GAP in directed cell movementComputer vision profiling of neurite outgrowth dynamics reveals spatiotemporal modularity of Rho GTPase signalingA Point Mutation in p190A RhoGAP Affects Ciliogenesis and Leads to Glomerulocystic Kidney DefectsCrystal structure of the breakpoint cluster region-homology domain from phosphoinositide 3-kinase p85 alpha subunitThe LIM domain-containing Dbm1 GTPase-activating protein is required for normal cellular morphogenesis in Saccharomyces cerevisiae.Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.Convergent use of RhoGAP toxins by eukaryotic parasites and bacterial pathogensRegulation of CDC42 GTPase by proline-rich tyrosine kinase 2 interacting with PSGAP, a novel pleckstrin homology and Src homology 3 domain containing rhoGAP protein.RHO binding to FAM65A regulates Golgi reorientation during cell migrationRho GTPases control polarity, protrusion, and adhesion during cell movementRegulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeletonRas-GAP controls Rho-mediated cytoskeletal reorganization through its SH3 domain.3BP-1, an SH3 domain binding protein, has GAP activity for Rac and inhibits growth factor-induced membrane ruffling in fibroblasts.Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS.A complex of p190RhoGAP-A and anillin modulates RhoA-GTP and the cytokinetic furrow in human cells.Cancer-associated mutations in the protrusion-targeting region of p190RhoGAP impact tumor cell migration.The human papillomavirus E7 proteins associate with p190RhoGAP and alter its function.Mitotic down-regulation of p190RhoGAP is required for the successful completion of cytokinesisThe Tumor Suppressor, p190RhoGAP, Differentially Initiates Apoptosis and Confers Docetaxel Sensitivity to Breast Cancer Cells.Extracellular signal-regulated kinase promotes Rho-dependent focal adhesion formation by suppressing p190A RhoGAP.p190RhoGAP negatively regulates Rho activity at the cleavage furrow of mitotic cells.Opposing roles of p190RhoGAP and Ect2 RhoGEF in regulating cytokinesis.Localized suppression of RhoA activity by Tyr31/118-phosphorylated paxillin in cell adhesion and migration.c-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulationp190RhoGAP can act to inhibit PDGF-induced gliomas in mice: a putative tumor suppressor encoded on human chromosome 19q13.3.Tyrosine 807 of the v-Fms oncogene product controls cell morphology and association with p120RasGAP.Cytoplasmic death signal triggered by SRC-mediated phosphorylation of the adenovirus E4orf4 protein.Phosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c-Src, is the sole p-Tyr mediator of complex formationRho activation is apically restricted by Arhgap1 in neural crest cells and drives epithelial-to-mesenchymal transition.Toward understanding RhoGTPase specificity: structure, function and local activation.RhoA GTPase inhibition organizes contraction during epithelial morphogenesis.HIV gp41 engages gC1qR on CD4+ T cells to induce the expression of an NK ligand through the PIP3/H2O2 pathway.Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers.
P2860
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P2860
rho family GTPase activating proteins p190, bcr and rhoGAP show distinct specificities in vitro and in vivo
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
rho family GTPase activating p ...... ificities in vitro and in vivo
@en
type
label
rho family GTPase activating p ...... ificities in vitro and in vivo
@en
prefLabel
rho family GTPase activating p ...... ificities in vitro and in vivo
@en
P2093
P2860
P1433
P1476
rho family GTPase activating p ...... ificities in vitro and in vivo
@en
P2093
P2860
P304
P407
P50
P577
1993-12-01T00:00:00Z