A role for PML and the nuclear body in genomic stability.
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PML nuclear bodiesNuclear structure in normal and Bloom syndrome cellsA new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrixRegulation and localization of the Bloom syndrome protein in response to DNA damageThe tripartite motif family identifies cell compartments.PML contributes to a cellular mechanism of repression of herpes simplex virus type 1 infection that is inactivated by ICP0Evidence for a role of the cellular ND10 protein PML in mediating intrinsic immunity against human cytomegalovirus infectionsPML colocalizes with and stabilizes the DNA damage response protein TopBP1PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2The Bloom's syndrome helicase stimulates the activity of human topoisomerase IIIalphaThe RecQ DNA helicases in DNA repairRepression of PML nuclear body-associated transcription by oxidative stress-activated Bach2Dominant negative mutations affect oligomerization of human pyruvate kinase M2 isozyme and promote cellular growth and polyploidyThe C-terminal domain of the Bloom syndrome DNA helicase is essential for genomic stabilityThe function, regulation and therapeutic implications of the tumor suppressor protein, PMLFunctional overlap between Sgs1-Top3 and the Mms4-Mus81 endonucleaseDisruption of SUMO-targeted ubiquitin ligases Slx5-Slx8/RNF4 alters RecQ-like helicase Sgs1/BLM localization in yeast and human cells.The transcriptional role of PML and the nuclear bodyFunctional interaction of p53 and BLM DNA helicase in apoptosisPotential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51Promyelocytic leukemia is a direct inhibitor of SAPK2/p38 mitogen-activated protein kinaseThe broken genome: genetic and pharmacologic approaches to breaking DNARecQ helicases: caretakers of the genomeChanging nuclear landscape and unique PML structures during early epigenetic transitions of human embryonic stem cells.Unwinding protein complexes in ALTernative telomere maintenance.Functional connection between Rad51 and PML in homology-directed repair.Selective cleavage of BLM, the bloom syndrome protein, during apoptotic cell death.Mapping the DNA topoisomerase III binding domain of the Sgs1 DNA helicase.A high-content screening (HCS) assay for the identification of chemical inducers of PML oncogenic domains (PODs).Role of the promyelocytic leukemia protein PML in the interferon sensitivity of lymphocytic choriomeningitis virus.Phosphorylation of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage.WRN, the protein deficient in Werner syndrome, plays a critical structural role in optimizing DNA repair.The role of post-translational modifications in fine-tuning BLM helicase function during DNA repairInhibition of long non-coding RNA NEAT1 impairs myeloid differentiation in acute promyelocytic leukemia cells.PML-mediated signaling and its role in cancer stem cells.In vivo analysis of the molecular genetics of acute promyelocytic leukemia.The theory of APL.Adenovirus early E4 genes in viral oncogenesis.Relapse of acute promyelocytic leukemia with PML-RARalpha mutant subclones independent of proximate all-trans retinoic acid selection pressureThe tumor suppressor PML specifically accumulates at RPA/Rad51-containing DNA damage repair foci but is nonessential for DNA damage-induced fibroblast senescence.
P2860
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P2860
A role for PML and the nuclear body in genomic stability.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
A role for PML and the nuclear body in genomic stability.
@en
type
label
A role for PML and the nuclear body in genomic stability.
@en
prefLabel
A role for PML and the nuclear body in genomic stability.
@en
P2093
P2860
P356
P1433
P1476
A role for PML and the nuclear body in genomic stability.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1203367
P407
P577
1999-12-01T00:00:00Z
P5875
P6179
1004042632