Identification of amino acids in the factor XI apple 3 domain required for activation of factor IX.
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Factor XI homodimer structure is essential for normal proteolytic activation by factor XIIa, thrombin, and factor XIaSolution structure of the A4 domain of factor XI sheds light on the mechanism of zymogen activationThe role of high molecular weight kininogen and prothrombin as cofactors in the binding of factor XI A3 domain to the platelet surfaceFunctional role of residue 193 (chymotrypsin numbering) in serine proteases: influence of side chain length and beta-branching on the catalytic activity of blood coagulation factor XIa.Structure and function of factor XIAnalysis of the factor XI variant Arg184Gly suggests a structural basis for factor IX binding to factor XIaDo platelets synthesize factor XI?Sulfated pentagalloylglucoside is a potent, allosteric, and selective inhibitor of factor XIaActivation of factor XI by products of prothrombin activationThe role of factor XIa (FXIa) catalytic domain exosite residues in substrate catalysis and inhibition by the Kunitz protease inhibitor domain of protease nexin 2A novel missense mutation Asp506Gly in Exon 13 of the F11 gene in an asymptomatic Korean woman with mild factor XI deficiency.Productive recognition of factor IX by factor XIa exosites requires disulfide linkage between heavy and light chains of factor XIa.A classification system for cross-reactive material-negative factor XI deficiencyA sequential mechanism for exosite-mediated factor IX activation by factor XIaExosite-mediated substrate recognition of factor IX by factor XIa. The factor XIa heavy chain is required for initial recognition of factor IX.Characterization of Novel Forms of Coagulation Factor XIa: independence of factor XIa subunits in factor IX activation.Characterization of a heparin-binding site on the catalytic domain of factor XIa: mechanism of heparin acceleration of factor XIa inhibition by the serpins antithrombin and C1-inhibitorEvolution of the contact phase of vertebrate blood coagulation.Factor XI contributes to thrombin generation in the absence of factor XIIUpdate on the physiology and pathology of factor IX activation by factor XIa.Structural and functional features of factor XI.Characterization of the H-kininogen-binding site on factor XI: a comparison of factor XI and plasma prekallikrein.Crystal structure of the factor XI zymogen reveals a pathway for transactivation.Evidence against a protein in plasma that is a product of a factor XI mRNA splice variant missing exons 6 and 7.Molecular cloning and biochemical characterization of rabbit factor XI.The factor IX gamma-carboxyglutamic acid (Gla) domain is involved in interactions between factor IX and factor XIa.Factor XI apple domains and protein dimerization.Structural role of Gly(193) in serine proteases: investigations of a G555E (GLY193 in chymotrypsin) mutant of blood coagulation factor XI.Severe factor XI deficiency caused by a Gly555 to Glu mutation (factor XI-Glu555): a cross-reactive material positive variant defective in factor IX activation.An update on factor XI structure and function.Molecular basis of severe factor XI deficiency in seven families from the west of France. Seven novel mutations, including an ancient Q88X mutation.Identification of a Binding Site for Glycoprotein Ibα in the Apple 3 Domain of Factor XI
P2860
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P2860
Identification of amino acids in the factor XI apple 3 domain required for activation of factor IX.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Identification of amino acids ...... d for activation of factor IX.
@en
type
label
Identification of amino acids ...... d for activation of factor IX.
@en
prefLabel
Identification of amino acids ...... d for activation of factor IX.
@en
P2093
P2860
P356
P1476
Identification of amino acids ...... d for activation of factor IX.
@en
P2093
P2860
P304
36373-36378
P356
10.1074/JBC.274.51.36373
P407
P577
1999-12-01T00:00:00Z