Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line.
about
Systematic identification of regulatory proteins critical for T-cell activationA BASH/SLP-76-related adaptor protein MIST/Clnk involved in IgE receptor-mediated mast cell degranulationAssociation of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signalingStructural and functional dissection of the cytoplasmic domain of the transmembrane adaptor protein SIT (SHP2-interacting transmembrane adaptor protein)T cell regulation of p62(dok) (Dok1) association with Crk-LThe importance of three membrane-distal tyrosines in the adaptor protein NTAL/LABMolecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signalingLAB: a new membrane-associated adaptor molecule in B cell activationMapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cellsDifferential role of glycolipid-enriched membrane domains in glycoprotein VI- and integrin-mediated phospholipase Cgamma2 regulation in plateletsPositive and negative regulation of T-cell activation through kinases and phosphatasesA PAK1-PIX-PKL complex is activated by the T-cell receptor independent of Nck, Slp-76 and LAT.Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFATDok-3, a novel adapter molecule involved in the negative regulation of immunoreceptor signalingRegulatory and signaling properties of the Vav familyT cell activationLIME, a novel transmembrane adaptor protein, associates with p56lck and mediates T cell activationRasGRF2, a guanosine nucleotide exchange factor for Ras GTPases, participates in T-cell signaling responsesRegulation of the human LAT gene by the Elf-1 transcription factorVav family exchange factors: an integrated regulatory and functional viewBiochemical interactions integrating Itk with the T cell receptor-initiated signaling cascadeThe adapter protein LAT enhances fcgamma receptor-mediated signal transduction in myeloid cellsLAT, the linker for activation of T cells: a bridge between T cell-specific and general signaling pathwaysIdentification of a new transmembrane adaptor protein that constitutively binds Grb2 in B cellsPhosphorylation site dynamics of early T-cell receptor signalingHematopoietic adaptors in T-cell signaling: potential applications to transplantationADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugationNck/Dock: an adapter between cell surface receptors and the actin cytoskeleton.MIST functions through distinct domains in immunoreceptor signaling in the presence and absence of LAT.SHP-1 and SHP-2 in T cells: two phosphatases functioning at many levelsRole of LAT in the granule-mediated cytotoxicity of CD8 T cells.Involvement of LAT, Gads, and Grb2 in compartmentation of SLP-76 to the plasma membranePleiotropic contributions of phospholipase C-gamma1 (PLC-gamma1) to T-cell antigen receptor-mediated signaling: reconstitution studies of a PLC-gamma1-deficient Jurkat T-cell lineDynamic palmitoylation and the role of DHHC proteins in T cell activation and anergy.The transmembrane adapter protein SIT regulates thymic development and peripheral T-cell functions.Membrane raft-dependent regulation of phospholipase Cgamma-1 activation in T lymphocytes.Zap-70-independent Ca(2+) mobilization and Erk activation in Jurkat T cells in response to T-cell antigen receptor ligation.Genetic evidence for Shc requirement in TCR-induced c-Rel nuclear translocation and IL-2 expression.The importance of LAT in the activation, homeostasis, and regulatory function of T cellsThe transmembrane adapter LAT plays a central role in immune receptor signalling.
P2860
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P2860
Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Functional analysis of LAT in ...... AT-deficient Jurkat cell line.
@en
type
label
Functional analysis of LAT in ...... AT-deficient Jurkat cell line.
@en
prefLabel
Functional analysis of LAT in ...... AT-deficient Jurkat cell line.
@en
P2093
P356
P1476
Functional analysis of LAT in ...... AT-deficient Jurkat cell line.
@en
P2093
P304
P356
10.1093/INTIMM/11.6.943
P577
1999-06-01T00:00:00Z