Limiting amounts of p27Kip1 correlates with constitutive activation of cyclin E-CDK2 complex in HTLV-I-transformed T-cells.
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HTLV-I p30 inhibits multiple S phase entry checkpoints, decreases cyclin E-CDK2 interactions and delays cell cycle progressionThe role of cyclin D2 and p21/waf1 in human T-cell leukemia virus type 1 infected cellsHTLV-1 Infection and Adult T-Cell Leukemia/Lymphoma-A Tale of Two Proteins: Tax and HBZTumor Suppressor Inactivation in the Pathogenesis of Adult T-Cell LeukemiaLife, death, and tax: role of HTLV-I oncoprotein in genetic instability and cellular transformationHTLV-I Tax-dependent and -independent events associated with immortalization of human primary T lymphocytes.NF-κB hyper-activation by HTLV-1 tax induces cellular senescence, but can be alleviated by the viral anti-sense protein HBZ.KSHV vCyclin counters the senescence/G1 arrest response triggered by NF-κB hyperactivation.Human T-cell lymphotropic virus type 1 Tax represses c-Myb-dependent transcription through activation of the NF-kappaB pathway and modulation of coactivator usage.Physical interaction of human T-cell leukemia virus type 1 Tax with cyclin-dependent kinase 4 stimulates the phosphorylation of retinoblastoma proteinHTLV-1 propels untransformed CD4 lymphocytes into the cell cycle while protecting CD8 cells from death.Activation of the anaphase promoting complex by HTLV-1 tax leads to senescence.Association of SRC-related kinase Lyn with the interleukin-2 receptor and its role in maintaining constitutive phosphorylation of JAK/STAT in human T-cell leukemia virus type 1-transformed T cells.HTLV-1 Tax mutants that do not induce G1 arrest are disabled in activating the anaphase promoting complex.Persistent inhibition of telomerase reprograms adult T-cell leukemia to p53-dependent senescence.HTLV-I Tax-Mediated Inactivation of Cell Cycle Checkpoints and DNA Repair Pathways Contribute to Cellular Transformation: "A Random Mutagenesis Model"Human T-cell leukemia virus type 1 infection leads to arrest in the G1 phase of the cell cycleHuman T Lymphotropic Virus Type I (HTLV-I) Oncogenesis: Molecular Aspects of Virus and Host Interactions in Pathogenesis of Adult T cell Leukemia/Lymphoma (ATL).Human T-lymphotropic virus proteins and post-translational modification pathwaysDownregulation of CDKN1A in adult T-cell leukemia/lymphoma despite overexpression of CDKN1A in human T-lymphotropic virus 1-infected cell lines.Accelerated G(1) phase progression induced by the human T cell leukemia virus type I (HTLV-I) Tax oncoprotein.HTLV-I Tax transrepresses the human c-Myb promoter independently of its interaction with CBP or p300.Human T-cell leukemia virus type I tax repression of p73beta is mediated through competition for the C/H1 domain of CBP.
P2860
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P2860
Limiting amounts of p27Kip1 correlates with constitutive activation of cyclin E-CDK2 complex in HTLV-I-transformed T-cells.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Limiting amounts of p27Kip1 co ...... in HTLV-I-transformed T-cells.
@en
type
label
Limiting amounts of p27Kip1 co ...... in HTLV-I-transformed T-cells.
@en
prefLabel
Limiting amounts of p27Kip1 co ...... in HTLV-I-transformed T-cells.
@en
P2093
P2860
P356
P1433
P1476
Limiting amounts of p27Kip1 co ...... in HTLV-I-transformed T-cells.
@en
P2093
Cereseto A
Franchini G
Rivadeneira E
Washington Parks R
P2860
P2888
P304
P356
10.1038/SJ.ONC.1202567
P407
P577
1999-04-01T00:00:00Z
P5875
P6179
1009175085