Matrilin-2, a large, oligomeric matrix protein, is expressed by a great variety of cells and forms fibrillar networks.
about
Identification and characterization of AMACO, a new member of the von Willebrand factor A-like domain protein superfamily with a regulated expression in the kidneyMatrilin-2 interacts with itself and with other extracellular matrix proteinsThrombospondin-4 binds specifically to both collagenous and non-collagenous extracellular matrix proteins via its C-terminal domainsFunctional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritisNormal skeletal development of mice lacking matrilin 1: redundant function of matrilins in cartilage?Extracellular deposition of matrilin-2 controls the timing of the myogenic program during muscle regeneration.Characterization of the matrilin coiled-coil domains reveals seven novel isoforms.Steroid and xenobiotic receptor SXR mediates vitamin K2-activated transcription of extracellular matrix-related genes and collagen accumulation in osteoblastic cells.Axonally derived matrilin-2 induces proinflammatory responses that exacerbate autoimmune neuroinflammation.Profiling of autoantibodies in IgA nephropathy, an integrative antibiomics approach.An invasion-independent pathway of blood-borne metastasis: a new murine mammary tumor model.Fibrillin-2, tenascin-C, matrilin-2, and matrilin-4 are strongly expressed in the epithelium of human granular and lattice type I corneal dystrophies.The matrilins--adaptor proteins in the extracellular matrix.Traffic jams in fish bones: ER-to-Golgi protein transport during zebrafish development.How to build an inducible cartilage-specific transgenic mouse.Sequential extracellular matrix-focused and baited-global cluster analysis of serial transcriptomic profiles identifies candidate modulators of renal tubulointerstitial fibrosis in murine adriamycin-induced nephropathy.Matrilin-2 is a widely distributed extracellular matrix protein and a potential biomarker in the early stage of osteoarthritis in articular cartilage.Lack of Matrilin-2 favors liver tumor development via Erk1/2 and GSK-3β pathways in vivo.Matrilin-2 is proteolytically cleaved by ADAMTS-4 and ADAMTS-5.Upregulation of matrilin-2 expression in murine hepatic stellate cells during liver injury has no effect on fibrosis formation and resolution.Matrilin-3 induction of IL-1 receptor antagonist is required for up-regulating collagen II and aggrecan and down-regulating ADAMTS-5 gene expression.Altered integration of matrilin-3 into cartilage extracellular matrix in the absence of collagen IX.The cysteine-rich domain of snake venom metalloproteinases is a ligand for von Willebrand factor A domains: role in substrate targeting.Role of epidermal growth factor receptor signaling in RAS-driven melanoma.Zebrafish (Danio rerio) matrilins: shared and divergent characteristics with their mammalian counterpartsMatrilin-3 is dispensable for mouse skeletal growth and development.Matrilin-2, an extracellular adaptor protein, is needed for the regeneration of muscle, nerve and other tissues.Molecular structure, processing, and tissue distribution of matrilin-4.Proteolytic processing causes extensive heterogeneity of tissue matrilin forms.Characterization of recombinantly expressed matrilin VWA domains.Analysis of the cartilage proteome from three different mouse models of genetic skeletal diseases reveals common and discrete disease signatures.The cartilage-specific lectin C-type lectin domain family 3 member A (CLEC3A) enhances tissue plasminogen activator-mediated plasminogen activation.Altered expression of genes for Kir ion channels in dilated cardiomyopathy.Downregulation of microRNA-448 inhibits IL-1β-induced cartilage degradation in human chondrocytes via upregulation of matrilin-3.
P2860
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P2860
Matrilin-2, a large, oligomeric matrix protein, is expressed by a great variety of cells and forms fibrillar networks.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Matrilin-2, a large, oligomeri ...... and forms fibrillar networks.
@en
type
label
Matrilin-2, a large, oligomeri ...... and forms fibrillar networks.
@en
prefLabel
Matrilin-2, a large, oligomeri ...... and forms fibrillar networks.
@en
P2093
P2860
P356
P1476
Matrilin-2, a large, oligomeri ...... s and forms fibrillar networks
@en
P2093
M Mörgelin
M Paulsson
P2860
P304
13353-13361
P356
10.1074/JBC.274.19.13353
P407
P577
1999-05-01T00:00:00Z