ATP- and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1.
about
Role of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analoguesATP-binding cassette (ABC) transporters in normal and pathological lungTargeting multidrug resistance in cancerA synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.Glutathione stimulates sulfated estrogen transport by multidrug resistance protein 1.Clerosterol from vinegar-baked radix bupleuri modifies drug transport.Role of the NH2-terminal membrane spanning domain of multidrug resistance protein 1/ABCC1 in protein processing and traffickingThe synthesis and characterization of cellular membrane affinity chromatography columns for the study of human multidrug resistant proteins MRP1, MRP2 and human breast cancer resistant protein BCRP using membranes obtained from Spodoptera frugiperdaMultidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier.Multidrug resistance-associated protein-1 (MRP1) genetic variants, MRP1 protein levels and severity of COPD.ABC drug transporters: hereditary polymorphisms and pharmacological impact in MDR1, MRP1 and MRP2.The structure of the multidrug resistance protein 1 (MRP1/ABCC1). crystallization and single-particle analysis.A family of drug transporters: the multidrug resistance-associated proteins.Intermediate structural states involved in MRP1-mediated drug transport. Role of glutathione.Marine sponge-derived sipholane triterpenoids reverse P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cellsPharmacokinetic and pharmacodynamic implications of P-glycoprotein modulation.Promoter polymorphism of MRP1 associated with reduced survival in hepatocellular carcinoma.The role of drug efflux pumps in acute myeloid leukemia.Active transport of the angiotensin-II antagonist losartan and its main metabolite EXP 3174 across MDCK-MDR1 and caco-2 cell monolayers.Drug transporters, the blood-testis barrier, and spermatogenesisDetection and characterisation of multi-drug resistance protein 1 (MRP-1) in human mitochondria.Inhibition of the MRP1-mediated transport of the menadione-glutathione conjugate (thiodione) in HeLa cells as studied by SECM.Enhanced combination therapy effect on paclitaxel-resistant carcinoma by chloroquine co-delivery via liposomesEndocrine and metabolic regulation of renal drug transporters.Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins.Drug-drug interactions involving membrane transporters in the human kidney.Redox regulation of multidrug resistance in cancer chemotherapy: molecular mechanisms and therapeutic opportunitiesDevelopment of inhibitors of ATP-binding cassette drug transporters: present status and challenges.Plasma membrane glutathione transporters and their roles in cell physiology and pathophysiologyMolecular abnormalities in Ewing's sarcoma.Physiological and pharmacological significance of glutathione-conjugate transport.Elevation of glutathione as a therapeutic strategy in Alzheimer disease.Multidrug resistance associated proteins in multidrug resistance.Intestinal transporters for endogenic and pharmaceutical organic anions: the challenges of deriving in-vitro kinetic parameters for the prediction of clinically relevant drug-drug interactions.Reversal of ATP-binding cassette drug transporter activity to modulate chemoresistance: why has it failed to provide clinical benefit?Multidrug resistance: Physiological principles and nanomedical solutions.Natural product modulators to overcome multidrug resistance in cancer.Mechanisms and therapeutic potential of inhibiting drug efflux transporters.Chronic toxicological effects of β-diketone antibiotics on Zebrafish (Danio rerio) using transcriptome profiling of deep sequencing.Placental ABC Transporters: Biological Impact and Pharmaceutical Significance.
P2860
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P2860
ATP- and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
ATP- and glutathione-dependent ...... idrug resistance protein MRP1.
@en
type
label
ATP- and glutathione-dependent ...... idrug resistance protein MRP1.
@en
prefLabel
ATP- and glutathione-dependent ...... idrug resistance protein MRP1.
@en
P2093
P2860
P356
P1476
ATP- and glutathione-dependent ...... tidrug resistance protein MRP1
@en
P2093
P2860
P304
P356
10.1038/SJ.BJP.0702360
P407
P577
1999-02-01T00:00:00Z