Spontaneous Ca waves in ventricular myocytes from failing hearts depend on Ca(2+)-calmodulin-dependent protein kinase II.
about
The role of late I Na in development of cardiac arrhythmiasIon Channels in the HeartAbnormal Ca(2+) cycling in failing ventricular myocytes: role of NOS1-mediated nitroso-redox balance'Ryanopathy': causes and manifestations of RyR2 dysfunction in heart failureCalmodulin-dependent protein kinase II: linking heart failure and arrhythmiasRole of sodium and calcium dysregulation in tachyarrhythmias in sudden cardiac death.Inherited dysfunction of sarcoplasmic reticulum Ca2+ handling and arrhythmogenesisSimulation and mechanistic investigation of the arrhythmogenic role of the late sodium current in human heart failureCaMKII-dependent responses to ischemia and reperfusion challenges in the heart.CaMKII regulation of cardiac ryanodine receptors and inositol triphosphate receptors.Toward a hierarchy of mechanisms in CaMKII-mediated arrhythmia.Store-dependent deactivation: cooling the chain-reaction of myocardial calcium signaling.Electrical defects of the transverse-axial tubular system in cardiac diseasesIntracellular translocation of calmodulin and Ca2+/calmodulin-dependent protein kinase II during the development of hypertrophy in neonatal cardiomyocytes.Ryanodine receptors: structure, expression, molecular details, and function in calcium release.Epac2 mediates cardiac β1-adrenergic-dependent sarcoplasmic reticulum Ca2+ leak and arrhythmia.Nitric oxide-dependent activation of CaMKII increases diastolic sarcoplasmic reticulum calcium release in cardiac myocytes in response to adrenergic stimulation.Coordinating electrical activity of the heart: ankyrin polypeptides in human cardiac disease.Electrophysiological and structural remodeling in heart failure modulate arrhythmogenesis. 1D simulation study.How does stochastic ryanodine receptor-mediated Ca leak fail to initiate a Ca spark?Calcium/calmodulin-dependent protein kinase II (CaMKII) inhibition ameliorates arrhythmias elicited by junctin ablation under stress conditionsOxidation of ryanodine receptor (RyR) and calmodulin enhance Ca release and pathologically alter, RyR structure and calmodulin affinity.T-Tubular Electrical Defects Contribute to Blunted β-Adrenergic Response in Heart Failure.Increased Energy Demand during Adrenergic Receptor Stimulation Contributes to Ca(2+) Wave Generation.Reduced response to IKr blockade and altered hERG1a/1b stoichiometry in human heart failureSarcoplasmic Reticulum Structure and Functional Properties that Promote Long-Lasting Calcium Sparks.Atrial remodelling in atrial fibrillation: CaMKII as a nodal proarrhythmic signalReduced Arrhythmia Inducibility With Calcium/Calmodulin-dependent Protein Kinase II Inhibition in Heart Failure RabbitsIsoproterenol increases the fraction of spark-dependent RyR-mediated leak in ventricular myocytes.Flecainide reduces Ca(2+) spark and wave frequency via inhibition of the sarcolemmal sodium current.Revisiting K(+) channel-dependent electrical remodeling in the border zone.The arrhythmogenic consequences of increasing late INa in the cardiomyocyte.The ryanodine receptor channel as a molecular motif in atrial fibrillation: pathophysiological and therapeutic implications.Inherited calcium channelopathies in the pathophysiology of arrhythmias.The promise of CaMKII inhibition for heart disease: preventing heart failure and arrhythmias.Regulation of sarcoplasmic reticulum Ca2+ release by serine-threonine phosphatases in the heart.Murine Electrophysiological Models of Cardiac Arrhythmogenesis.Mechanistic and therapeutic perspectives for cardiac arrhythmias: beyond ion channels.Calcium and Excitation-Contraction Coupling in the HeartCaMKII-dependent phosphorylation of RyR2 promotes targetable pathological RyR2 conformational shift.
P2860
Q26823149-AD02BF63-3E6F-4522-8BC3-7E455AAD5CD1Q26829681-48D5748E-7AA3-4261-A663-B64998CE3054Q26852587-95E0AA61-F938-47EE-B85A-9B7FBD76C92FQ26865421-5CB49241-4551-4B63-9C52-58EF7AE141D4Q26999872-A14930FA-AA43-4AC3-8848-8E5C611C8A80Q27339434-2BA25C8F-6053-41F5-8FA2-3B4B3D2CCA0FQ28308142-473EA3FD-27BA-4187-891B-FEA9C5818E78Q28731387-43643162-1CDD-45CC-8568-1BE5EF1BC6C5Q33600515-D97CA2DE-4731-4354-BC94-34433B30A86FQ33611715-556A1999-188C-4312-9D01-EC5D8D7BA403Q33775402-44028239-C4D3-44EB-91A8-AD2E15AF538AQ33798663-D961A318-A27C-4C27-B19D-68789EC79D00Q33800163-F87830DD-CC4C-4154-8BBC-1A65F5153096Q33886760-67948210-E744-4869-BA35-711C82D917C4Q34024377-32F37A70-5A02-4FD7-B692-D68774EE56A0Q34325276-E2AA68B6-D34C-45D4-B184-386CCE9ABA1CQ35086912-43E841FB-0447-4124-970F-915419D9CD6FQ35195291-0C89942D-A165-43FE-BBB4-B9E1D1C8176AQ35239679-FA53B0B0-7010-4FF7-922B-B42D87F9E4BFQ35556363-2613815D-2685-43DD-A0B7-2C4CE6162934Q35798054-53EE290B-FD68-462F-8E8B-FDC62437A250Q35931379-8800A75B-BD65-46A8-B59A-81C7FCCF1864Q36123708-B2F060FE-80FA-430D-BC90-605E5481CA94Q36219325-F79AEF6F-FB56-4BDF-BC51-E8142A2E51F5Q36381497-29F935CA-4C25-417C-909A-E8FCD33547F0Q36495468-FB859B60-84AF-4C0B-A50C-9A4BBCD9B13BQ36650585-6B8B2CEB-8E03-4C2A-BEAB-6D73CEACDBD1Q36665177-4071D3E1-2EFD-468B-8DDA-5422594B2AB9Q36665430-4CCF792E-4402-4FDD-B82C-8DDBA1B02EF0Q37023408-5FF7127D-C9F3-492E-B0F0-0EB3B97EE2C5Q37325502-9D0EF117-8B83-46AF-81B0-9C392F38D201Q37345048-70B4AAA0-310D-4D12-AE0E-0076ABB576D3Q37799958-169B088D-58B9-4DD7-A5C5-8668BBC1AF14Q38021673-2EFD8DDE-2BDF-488D-A22D-640BFEB3F2D3Q38116041-83664F56-433F-4741-B691-9F64EA5B6A8DQ38944079-80729A46-5C53-476A-BDF5-315898D780D3Q39038606-0BBE9A2B-5869-4122-94FE-076ECC35CE92Q39204197-AA81165F-D937-4303-9261-6F60E975CA20Q39419376-8E129924-9CEC-4355-88EE-331C15B7F342Q41112224-795705A6-6AA4-4214-B287-012E547968A9
P2860
Spontaneous Ca waves in ventricular myocytes from failing hearts depend on Ca(2+)-calmodulin-dependent protein kinase II.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Spontaneous Ca waves in ventri ...... n-dependent protein kinase II.
@en
type
label
Spontaneous Ca waves in ventri ...... n-dependent protein kinase II.
@en
prefLabel
Spontaneous Ca waves in ventri ...... n-dependent protein kinase II.
@en
P2093
P2860
P1476
Spontaneous Ca waves in ventri ...... in-dependent protein kinase II
@en
P2093
Jerry Curran
Kathy Hayes Brown
Steve Pogwizd
Thomas R Shannon
P2860
P356
10.1016/J.YJMCC.2010.03.013
P577
2010-03-29T00:00:00Z