Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3
about
Identification of a region within the ErbB2/HER2 intracellular domain that is necessary for ligand-independent associationThe ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous systemErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptorInsights into HER2 signaling from step-by-step optimization of anti-HER2 antibodiesIdentification of a heregulin binding site in HER3 extracellular domainMutation of a Shc binding site tyrosine residue in ErbB3/HER3 blocks heregulin-dependent activation of mitogen-activated protein kinaseHeregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinaseErbB tyrosine kinases and the two neuregulin families constitute a ligand-receptor network.Role of HER2 gene overexpression in breast carcinoma.Two EGF molecules contribute additively to stabilization of the EGFR dimerBivalence of EGF-like ligands drives the ErbB signaling networkExtracellular domains drive homo- but not hetero-dimerization of erbB receptorsThe oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesisA system for quantifying dynamic protein interactions defines a role for Herceptin in modulating ErbB2 interactions.Protein kinases in mammary gland development and cancer.Role of HER receptors family in development and differentiation.Characterization of protein-protein interactions involved in iron reduction by Shewanella oneidensis MR-1.Ligand-induced ErbB receptor dimerization.A discrete three-amino acid segment (LVI) at the C-terminal end of kinase-impaired ErbB3 is required for transactivation of ErbB2.Heregulin induces resistance to lapatinib-mediated growth inhibition of HER2-amplified cancer cells.Suppression of heregulin β signaling by the single N-glycan deletion mutant of soluble ErbB3 protein.The N-terminal domains of neuregulin 1 confer signal attenuation.Oligomers of ERBB3 have two distinct interfaces that differ in their sensitivity to disruption by heregulin.Formation of a high affinity heregulin binding site using the soluble extracellular domains of ErbB2 with ErbB3 or ErbB4.Her2 activation mechanism reflects evolutionary preservation of asymmetric ectodomain dimers in the human EGFR family.Signal transduction by epidermal growth factor and heregulin via the kinase-deficient ErbB3 protein.The single transmembrane domains of ErbB receptors self-associate in cell membranes.Size-exclusion chromatography with on-line light scattering.Neuregulin-1 and human epidermal growth factor receptors 2 and 3 play a role in human lung development in vitro.
P2860
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P2860
Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3
description
1995 nî lūn-bûn
@nan
1995 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3
@ast
Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3
@en
Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3
@en-gb
Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3
@nl
type
label
Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3
@ast
Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3
@en
Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3
@en-gb
Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3
@nl
prefLabel
Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3
@ast
Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3
@en
Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3
@en-gb
Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3
@nl
P2093
P2860
P356
P1476
Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3
@en
P2093
P2860
P304
P356
10.1074/JBC.270.41.24604
P407
P577
1995-10-13T00:00:00Z