Integrin-linked protein kinase regulates fibronectin matrix assembly, E-cadherin expression, and tumorigenicity.
about
Cloning of an isoform of integrin-linked kinase (ILK) that is upregulated in HT-144 melanoma cells following TGF-beta1 stimulationA new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreadingModulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1.The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cellsNck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathwaysA novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interactionPhosphorylation regulates the subcellular location and activity of the snail transcriptional repressorPhosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinaseElevated levels of beta-catenin and fibronectin in three-dimensional collagen cultures of Dupuytren's disease cells are regulated by tension in vitroIncreased expression of integrin-linked kinase is associated with shorter survival in non-small cell lung cancerInvolvement of integrin-linked kinase in capillary/tube-like network formation of human vascular endothelial cells.Integrin-linked kinase regulates interphase and mitotic microtubule dynamicsDysregulation of integrin-linked kinase (ILK) signaling in colonic polyposisThe paxillin LD motifsIntegrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesionsInhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cellsThe distribution and regulation of integrin-linked kinase in normal and diabetic kidneysCell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathwaysSubchronic exposure to arsenic through drinking water alters expression of cancer-related genes in rat liverFibronectin polymerization regulates the composition and stability of extracellular matrix fibrils and cell-matrix adhesions.Integrin-linked kinase in the vascular smooth muscle cell response to injuryIntegrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulationReduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytesPhosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells.Tensin 2 modulates cell contractility in 3D collagen gels through the RhoGAP DLC1.Integrin-linked kinase controls neurite outgrowth in N1E-115 neuroblastoma cells.SPARC regulates extracellular matrix organization through its modulation of integrin-linked kinase activity.Culture of K562 human myeloid leukemia cells in presence of fibronectin expresses and secretes MMP-9 in serum-free culture medium.Integration of cell attachment, cytoskeletal localization, and signaling by integrin-linked kinase (ILK), CH-ILKBP, and the tumor suppressor PTEN.Fibronectin matrix turnover occurs through a caveolin-1-dependent process.Modulation of cellular apoptotic potential: contributions to oncogenesis.PI-3 kinase activity is required for epithelial-mesenchymal transformation during palate fusion.Nicotine inhibits palatal fusion and modulates nicotinic receptors and the PI-3 kinase pathway in medial edge epitheliaImpact of PINCH expression on survival in colorectal cancer patients.Angiopoietin-2 stimulates breast cancer metastasis through the alpha(5)beta(1) integrin-mediated pathwayArchitectural transcription factor HMGI(Y) promotes tumor progression and mesenchymal transition of human epithelial cells.Role of epithelial integrin-linked kinase in promoting intestinal inflammation: effects on CCL2, fibronectin and the T cell repertoire.Molecular dissection of actopaxin-integrin-linked kinase-Paxillin interactions and their role in subcellular localization.All-trans retinoic acid (ATRA) downregulates MMP-9 by modulating its regulatory moleculesILKAP regulates ILK signaling and inhibits anchorage-independent growth.
P2860
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P2860
Integrin-linked protein kinase regulates fibronectin matrix assembly, E-cadherin expression, and tumorigenicity.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Integrin-linked protein kinase ...... xpression, and tumorigenicity.
@en
type
label
Integrin-linked protein kinase ...... xpression, and tumorigenicity.
@en
prefLabel
Integrin-linked protein kinase ...... xpression, and tumorigenicity.
@en
P2093
P2860
P356
P1476
Integrin-linked protein kinase ...... xpression, and tumorigenicity.
@en
P2093
C Leung-Hagesteijn
M Coppolino
S Goicoechea
S Y Keightley
P2860
P304
P356
10.1074/JBC.273.1.528
P407
P577
1998-01-01T00:00:00Z