CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.
about
Structural mechanism of trimeric HIV-1 envelope glycoprotein activationRoles of CD4 and coreceptors in binding, endocytosis, and proteolysis of gp120 envelope glycoproteins derived from human immunodeficiency virus type 1Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalizationCCR5 monoclonal antibodies for HIV-1 therapySpontaneous mutations in the env gene of the human immunodeficiency virus type 1 NDK isolate are associated with a CD4-independent entry phenotype.An orphan G protein-coupled receptor, GPR1, acts as a coreceptor to allow replication of human immunodeficiency virus types 1 and 2 in brain-derived cellsComprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodiesAccess of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infectionInfection of cells expressing CXCR4 mutants lacking N-glycosylation at the N-terminal extracellular domain is enhanced for R5X4-dualtropic human immunodeficiency virus type-1.Inhibition of human immunodeficiency virus type-1 (HIV-1) glycoprotein-mediated cell-cell fusion by immunor (IM28)Cellulose acetate phthalate, a common pharmaceutical excipient, inactivates HIV-1 and blocks the coreceptor binding site on the virus envelope glycoprotein gp120Antigenic properties of the human immunodeficiency virus envelope glycoprotein gp120 on virions bound to target cellsThe human immunodeficiency virus type 1 gp120 V2 domain mediates gp41-independent intersubunit contacts.Identification of a Residue in Hepatitis C Virus E2 Glycoprotein That Determines Scavenger Receptor BI and CD81 Receptor Dependency and Sensitivity to Neutralizing AntibodiesEbolavirus glycoprotein structure and mechanism of entryRational engineering of a miniprotein that reproduces the core of the CD4 site interacting with HIV-1 envelope glycoproteinCombinatorial Optimization of a CD4-Mimetic Miniprotein and Cocrystal Structures with HIV-1 gp120 Envelope GlycoproteinStructural improvement of unliganded simian immunodeficiency virus gp120 core by normal-mode-based X-ray crystallographic refinementCrystal Structure of the HIV-2 Neutralizing Fab Fragment 7C8 with High Specificity to the V3 Region of gp125The Conformation and Orientation of a 27-Residue CCR5 Peptide in a Ternary Complex with HIV-1 gp120 and a CD4-Mimic PeptideBroadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding GlycansInterfacial Cavity Filling To Optimize CD4–Mimetic Miniprotein Interactions with HIV-1 Surface GlycoproteinFine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120.Determinants of HIV-1 coreceptor function on CC chemokine receptor 3. Importance of both extracellular and transmembrane/cytoplasmic regionsAntibody potency relates to the ability to recognize the closed, pre-fusion form of HIV EnvThe antigenic structure of the HIV gp120 envelope glycoproteinThe good and evil of complement activation in HIV-1 infectionPeptide ligands to human immunodeficiency virus type 1 gp120 identified from phage display librariesInhibitory mechanism of the CXCR4 antagonist T22 against human immunodeficiency virus type 1 infection.Specific interaction of CCR5 amino-terminal domain peptides containing sulfotyrosines with HIV-1 envelope glycoprotein gp120Sensitivity of human immunodeficiency virus type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptorInhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4Resistance to a drug blocking human immunodeficiency virus type 1 entry (RPR103611) is conferred by mutations in gp41T-cell-line-tropic human immunodeficiency virus type 1 that is made resistant to stromal cell-derived factor 1alpha contains mutations in the envelope gp120 but does not show a switch in coreceptor useAnalysis of physicochemical and structural properties determining HIV-1 coreceptor usageA Cinnamon-Derived Procyanidin Compound Displays Anti-HIV-1 Activity by Blocking Heparan Sulfate- and Co-Receptor- Binding Sites on gp120 and Reverses T Cell Exhaustion via Impeding Tim-3 and PD-1 UpregulationHuman immunodeficiency virus strains differ in their ability to infect CD4+ cells expressing the rat homolog of CXCR-4 (fusin)CCR5 HIV-1 coreceptor activity. Role of cooperativity between residues in N-terminal extracellular and intracellular domainsHuman immunodeficiency virus (HIV) envelope binds to CXCR4 independently of CD4, and binding can be enhanced by interaction with soluble CD4 or by HIV envelope deglycosylation.
P2860
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P2860
CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.
@en
type
label
CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.
@en
prefLabel
CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.
@en
P2093
P356
P1433
P1476
CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.
@en
P2093
Allaway GP
Cheng-Mayer C
Robinson J
P2888
P304
P356
10.1038/384184A0
P407
P577
1996-11-01T00:00:00Z
P6179
1036628325