Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene.
about
Interaction of the mu-opioid receptor with GPR177 (Wntless) inhibits Wnt secretion: potential implications for opioid dependenceMOR is not enough: identification of novel mu-opioid receptor interacting proteins using traditional and modified membrane yeast two-hybrid screensA novel alternatively spliced isoform of the mu-opioid receptor: functional antagonismNocistatin, a peptide that blocks nociceptin action in pain transmissionClinically employed opioid analgesics produce antinociception via μ-δ opioid receptor heteromers in Rhesus monkeysRegulation of opioid tolerance by let-7 family microRNA targeting the mu opioid receptorImpaired emotional-like behavior and serotonergic function during protracted abstinence from chronic morphineDiscovery of positive allosteric modulators and silent allosteric modulators of the μ-opioid receptorHeteromerization of G protein-coupled receptors: relevance to neurological disorders and neurotherapeutics.Unidirectional cross-activation of GRPR by MOR1D uncouples itch and analgesia induced by opioidsMorphine-induced physiological and behavioral responses in mice lacking G protein-coupled receptor kinase 6Improvement of morphine-mediated analgesia by inhibition of β-arrestin2 expression in mice periaqueductal gray matterNeurokinin 1 receptors regulate morphine-induced endocytosis and desensitization of mu-opioid receptors in CNS neuronsMorphine-stimulated nitric oxide release in rabbit aqueous humorDrug discovery: Designing the ideal opioidAutism Spectrum Disorders and Drug Addiction: Common Pathways, Common Molecules, Distinct Disorders?15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuseAntibodies to probe endogenous G protein-coupled receptor heteromer expression, regulation, and functionTelomeres and epigenetics: potential relevance to chronic painOpioid receptors: toward separation of analgesic from undesirable effectsOpioid receptor heteromers in analgesiaPositive allosteric modulators of the μ-opioid receptor: a novel approach for future pain medicationsCrystal structure of the µ-opioid receptor bound to a morphinan antagonistCurrent research on opioid receptor function.Heterodimerization of mu and delta opioid receptors: A role in opiate synergyCrh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndromeActivity of mu- and delta-opioid agonists in vas deferens from mice deficient in MOR geneReduction of opioid dependence by the CB(1) antagonist SR141716A in mice: evaluation of the interest in pharmacotherapy of opioid addictionCyclophosphamide cystitis in mice: behavioural characterisation and correlation with bladder inflammationDisruption of the kappa-opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective kappa-agonist U-50,488H and attenuates morphine withdrawalMu and delta opioid receptors oppositely regulate motor impulsivity in the signaled nose poke taskLigand-directed functional selectivity at the mu opioid receptor revealed by label-free integrative pharmacology on-targetA growth factor attenuates HIV-1 Tat and morphine induced damage to human neurons: implication in HIV/AIDS-drug abuse casesMu opioid receptors on primary afferent nav1.8 neurons contribute to opiate-induced analgesia: insight from conditional knockout miceMembrane glycoprotein M6a interacts with the micro-opioid receptor and facilitates receptor endocytosis and recyclingDifferential regulation of prohormone convertase 1/3, prohormone convertase 2 and phosphorylated cyclic-AMP-response element binding protein by short-term and long-term morphine treatment: implications for understanding the "switch" to opiate addictAdenosine A2a blockade prevents synergy between mu-opiate and cannabinoid CB1 receptors and eliminates heroin-seeking behavior in addicted ratsOpioid-induced decreases in rat brain adenosine levels are reversed by inhibiting adenosine deaminaseSialorphin, a natural inhibitor of rat membrane-bound neutral endopeptidase that displays analgesic activityAbsence of opiate rewarding effects in mice lacking dopamine D2 receptors
P2860
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P2860
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Loss of morphine-induced analg ...... g the mu-opioid-receptor gene.
@en
type
label
Loss of morphine-induced analg ...... g the mu-opioid-receptor gene.
@en
prefLabel
Loss of morphine-induced analg ...... g the mu-opioid-receptor gene.
@en
P2093
P356
P1433
P1476
Loss of morphine-induced analg ...... g the mu-opioid-receptor gene.
@en
P2093
B L Kieffer
B P Roques
H W Matthes
P2888
P304
P356
10.1038/383819A0
P407
P577
1996-10-01T00:00:00Z
P6179
1008426943