Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice.
about
Human Th1 cells that express CD300a are polyfunctional and after stimulation up-regulate the T-box transcription factor eomesoderminCharged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12Mast cell homeostasis and the JAK-STAT pathwayFollicular helper T cells: lineage and locationGlobal mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cellsSelective expression of an interleukin-12 receptor component by human T helper 1 cellsA natural mutation in the Tyk2 pseudokinase domain underlies altered susceptibility of B10.Q/J mice to infection and autoimmunityHlx homeobox transcription factor negatively regulates interferon-gamma production in monokine-activated natural killer cellsTargeted disruption of the mouse Stat3 gene leads to early embryonic lethalitySignaling by STATsJanus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation.Cell fate decision: T-helper 1 and 2 subsets in immune responses.Signal transducer and activator of transcription 4 in liver diseasesSTAT4 requires the N-terminal domain for efficient phosphorylationPIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4Involvement of receptor-interacting protein 2 in innate and adaptive immune responsesRecent advances in the genetics of autoimmune diseaseAn updated view on transcription factor GATA3-mediated regulation of Th1 and Th2 cell differentiationLyn associates with the juxtamembrane region of c-Kit and is activated by stem cell factor in hematopoietic cell lines and normal progenitor cellsIdentification of a STAT4 binding site in the interleukin-12 receptor required for signalingDifferential associations between the cytoplasmic regions of the interleukin-12 receptor subunits beta1 and beta2 and JAK kinasesResidual type 1 immunity in patients genetically deficient for interleukin 12 receptor beta1 (IL-12Rbeta1): evidence for an IL-12Rbeta1-independent pathway of IL-12 responsiveness in human T cellsHemp, an mbt domain-containing protein, plays essential roles in hematopoietic stem cell function and skeletal formationDefective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient miceIdentification and characterization of SKAT-2, a novel Th2-specific zinc finger geneStat5b is essential for natural killer cell-mediated proliferation and cytolytic activitySTAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferationThe transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon-gammaPhosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformationRecruitment of Stat4 to the human interferon-alpha/beta receptor requires activated Stat2Opposing roles of STAT4 and Dnmt3a in Th1 gene regulationDifferentiation of effector CD4 T cell populations (*)Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficient miceLocation of CD4+ T cell priming regulates the differentiation of Th1 and Th17 cells and their contribution to arthritis.Inflammatory blockade improves human pancreatic islet function and viability.Activation of the 12-lipoxygenase and signal transducer and activator of transcription pathway during neointima formation in a model of the metabolic syndrome.IL-18-stimulated GADD45 beta required in cytokine-induced, but not TCR-induced, IFN-gamma production.Physical and functional interactions between STAP-2/BKS and STAT5.Specificity of signaling by hematopoietic cytokine receptors: instructive versus permissive effects.Involvement of STAT4 in IgG subtype switching and ocular HSV-1 replication in mice
P2860
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P2860
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice.
@en
type
label
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice.
@en
prefLabel
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice.
@en
P2093
P356
P1433
P1476
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice.
@en
P2093
P2888
P304
P356
10.1038/382174A0
P407
P577
1996-07-01T00:00:00Z
P5875
P6179
1051059793