Cushing's disease preceded by generalized glucocorticoid resistance: clinical consequences of a novel, dominant-negative glucocorticoid receptor mutation.
about
The non-ligand binding beta-isoform of the human glucocorticoid receptor (hGR beta): tissue levels, mechanism of action, and potential physiologic roleGeneralized glucocorticoid resistance: clinical aspects, molecular mechanisms, and implications of a rare genetic disorderPituitary adenomas: historical perspective, surgical management and future directionsChrousos syndrome: a seminal report, a phylogenetic enigma and the clinical implications of glucocorticoid signalling changesRho family Guanine nucleotide exchange factor Brx couples extracellular signals to the glucocorticoid signaling systemOvernight ACTH-cortisol dose responsiveness: comparison with 24-h data, metyrapone administration and insulin-tolerance test in healthy adults.Motivations and methods for analyzing pulsatile hormone secretionA novel point mutation of the human glucocorticoid receptor gene causes primary generalized glucocorticoid resistance through impaired interaction with the LXXLL motif of the p160 coactivators: dissociation of the transactivating and transreppressivThe human glucocorticoid receptor: molecular basis of biologic functionFamilial glucocorticoid resistance caused by a novel frameshift glucocorticoid receptor mutation.Primary generalized familial and sporadic glucocorticoid resistance (Chrousos syndrome) and hypersensitivityRecent advances in the molecular mechanisms determining tissue sensitivity to glucocorticoids: novel mutations, circadian rhythm and ligand-induced repression of the human glucocorticoid receptor.Glucocorticoid receptor mutants demonstrate increased motility inside the nucleus of living cells: time of fluorescence recovery after photobleaching (FRAP) is an integrated measure of receptor function.Recurrent gain-of-function USP8 mutations in Cushing's disease.The role of functional single nucleotide polymorphisms of the human glucocorticoid receptor gene NR3C1 in Polish patients with bronchial asthma.The Gene of the Ubiquitin-Specific Protease 8 Is Frequently Mutated in Adenomas Causing Cushing's Disease.The HIV-1 virion-associated protein vpr is a coactivator of the human glucocorticoid receptor.Structural Analysis on the Pathologic Mutant Glucocorticoid Receptor Ligand-Binding Domains.The glucocorticoid receptor and its expression in the anterior pituitary and the adrenal cortex: a source of variation in hypothalamic-pituitary-adrenal axis function; implications for pituitary and adrenal tumors.Gene mutations in Cushing's disease.Lack of mutations in the gene coding for the hGR (NR3C1) in a pediatric patient with ACTH-secreting pituitary adenoma, absence of stigmata of Cushing's syndrome and unusual histologic features.Genetics of Cushing's Syndrome.An unexpected, mild phenotype of glucocorticoid resistance associated with glucocorticoid receptor gene mutation case report and review of the literature.Recent advances in understanding corticotroph pituitary tumor initiation and progression
P2860
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P2860
Cushing's disease preceded by generalized glucocorticoid resistance: clinical consequences of a novel, dominant-negative glucocorticoid receptor mutation.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Cushing's disease preceded by ...... cocorticoid receptor mutation.
@en
type
label
Cushing's disease preceded by ...... cocorticoid receptor mutation.
@en
prefLabel
Cushing's disease preceded by ...... cocorticoid receptor mutation.
@en
P2093
P1476
Cushing's disease preceded by ...... ucocorticoid receptor mutation
@en
P2093
Chrousos GP
Huizenga NE
Lamberts SW
P304
P577
1996-07-01T00:00:00Z