Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells.
about
Pluripotent stem cell derived hepatocytes: using materials to define cellular differentiation and tissue engineeringInvestigating core genetic-and-epigenetic cell cycle networks for stemness and carcinogenic mechanisms, and cancer drug design using big database mining and genome-wide next-generation sequencing dataStem cell-derived models to improve mechanistic understanding and prediction of human drug-induced liver injuryPatient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicityDefinition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests.Recombinant Laminins Drive the Differentiation and Self-Organization of hESC-Derived HepatocytesHighlight report: Erroneous sample annotation in a high fraction of publicly available genome-wide expression datasetsCell sources for in vitro human liver cell culture models.Prediction of Differentiation Tendency Toward Hepatocytes from Gene Expression in Undifferentiated Human Pluripotent Stem Cells.Drug-induced mitochondrial impairment in liver cells.Transcriptomic signature for drug-induced steatosis.Expression classifiers for developmental toxicants.Highlight report: New methods for quantification of bile canalicular dynamics.Identification of carcinogens by a selected panel of DNA damage response associated genes.Systems Toxicology.Pluripotent stem cells to hepatocytes, the journey so far.The role of epigenetic modifiers in extended cultures of functional hepatocyte-like cells derived from human neonatal mesenchymal stem cells.Stable Overexpression of the Constitutive Androstane Receptor Reduces the Requirement for Culture with Dimethyl Sulfoxide for High Drug Metabolism in HepaRG Cells.Concise Review: Advances in Generating Hepatocytes from Pluripotent Stem Cells for Translational Medicine.Assessment of engineered cells using CellNet and RNA-seq.Toxicity testing and drug screening using iPSC-derived hepatocytes, cardiomyocytes, and neural cells.Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue.Highlight report: Cardiotoxicity screening.Hepatic Differentiation of Human Induced Pluripotent Stem Cells in a Perfused Three-Dimensional Multicompartment Bioreactor.Effects of Co-Culture Media on Hepatic Differentiation of hiPSC with or without HUVEC Co-Culture.Fluid shear stress modulation of hepatocyte-like cell function.H3K27me3 Does Not Orchestrate the Expression of Lineage-Specific Markers in hESC-Derived Hepatocytes In VitroHighlight report: biomarkers of acetaminophen-induced liver injury.Highlight report: xenobiotic-metabolizing enzymes in skin models.Dynamic regulation of EZH2 from HPSc to hepatocyte-like cell fate.Fabrication of low-cost micropatterned polydimethyl-siloxane scaffolds to organise cells in a variety of two-dimensioanl biomimetic arrangements for lab-on-chip culture platforms.Hepatic differentiation of human iPSCs in different 3D models: A comparative study.Distinct Gene Expression and Epigenetic Signatures in Hepatocyte-like Cells Produced by Different Strategies from the Same Donor.Comparative transcriptomics of hepatic differentiation of human pluripotent stem cells and adult human liver tissue.Highlight report: prediction of drug induced liver injury (DILI) with human hepatocytes in vitro.Stem cells in toxicological research.Mass production of stem cell derived human hepatocytes for experimental medicine.The Human Protein Atlas - an important resource for basic and clinical research.Highlight report: pluripotent stem cells in translational research.Designer human tissue: coming to a lab near you.
P2860
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P2860
Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Gene networks and transcriptio ...... ls into hepatocyte-like cells.
@en
type
label
Gene networks and transcriptio ...... ls into hepatocyte-like cells.
@en
prefLabel
Gene networks and transcriptio ...... ls into hepatocyte-like cells.
@en
P2093
P2860
P50
P1476
Gene networks and transcriptio ...... lls into hepatocyte-like cells
@en
P2093
Agata Widera
Andreas Nüssler
Annika Asplund
Baltasar Lucendo-Villarin
Barbara Küppers-Munther
Dagmara Szkolnicka
David C Hay
Georg Damm
Gisela Campos
Jane Synnergren
P2860
P304
P356
10.1016/J.JHEP.2015.05.013
P577
2015-05-25T00:00:00Z