Granulocyte-macrophage colony-stimulating factor provokes RAS activation and transcription of c-fos through different modes of signaling.
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Involvement of Hgs/Hrs in signaling for cytokine-mediated c-fos induction through interaction with TAK1 and Pak1New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathwaySHP1 and SHP2 protein-tyrosine phosphatases associate with betac after interleukin-3-induced receptor tyrosine phosphorylation. Identification of potential binding sites and substratesRal is both necessary and sufficient for the inhibition of myeloid differentiation mediated by RasCytoplasmic domains of the common beta-chain of the GM-CSF/IL-3/IL-5 receptors that are required for inducing differentiation or clonal suppression in myeloid leukaemic cell lines.IL-3 signaling and the role of Src kinases, JAKs and STATs: a covert liaison unveiled.The role of interchain heterodisulfide formation in activation of the human common beta and mouse betaIL-3 receptors.Janus kinases: components of multiple signaling pathways.The cytoplasmic domain of granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor alpha subunit is essential for both GM-CSF-mediated growth and differentiation.Cooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation.Cross-talk between ICAM-1 and granulocyte-macrophage colony-stimulating factor receptor signaling modulates eosinophil survival and activation.The molecular basis of IL-21-mediated proliferation.The Shc-binding site of the betac subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesisSrc homology 2 protein tyrosine phosphatase (SHPTP2)/Src homology 2 phosphatase 2 (SHP2) tyrosine phosphatase is a positive regulator of the interleukin 5 receptor signal transduction pathways leading to the prolongation of eosinophil survival.Activation and functional analysis of Janus kinase 2 in BA/F3 cells using the coumermycin/gyrase B system.Two distinct signaling pathways downstream of Janus kinase 2 play redundant roles for antiapoptotic activity of granulocyte-macrophage colony-stimulating factor.Definition of the role of tyrosine residues of the common beta subunit regulating multiple signaling pathways of granulocyte-macrophage colony-stimulating factor receptorDifferential utilization of Ras signaling pathways by macrophage colony-stimulating factor (CSF) and granulocyte-macrophage CSF receptors during macrophage differentiation.Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinaseThe Ig-like domain of human GM-CSF receptor alpha plays a critical role in cytokine binding and receptor activation.The role of disulfide-linked dimerization in interleukin-3 receptor signaling and biological activity.Regulation and function of protein kinase B and MAP kinase activation by the IL-5/GM-CSF/IL-3 receptor.Constitutive activation of JAK2 confers murine interleukin-3-independent survival and proliferation of BA/F3 cells.The kinase domain of Jak2 mediates induction of bcl-2 and delays cell death in hematopoietic cells.JAK2 is essential for activation of c-fos and c-myc promoters and cell proliferation through the human granulocyte-macrophage colony-stimulating factor receptor in BA/F3 cells.Gingival Tissue Inflammation Promotes Increased Matrix Metalloproteinase-12 Production by CD200Rlow Monocyte-Derived Cells in Periodontitis.Regulation of T-Cell Signaling by Post-Translational Modifications in Autoimmune Disease.
P2860
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P2860
Granulocyte-macrophage colony-stimulating factor provokes RAS activation and transcription of c-fos through different modes of signaling.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Granulocyte-macrophage colony- ...... different modes of signaling.
@en
type
label
Granulocyte-macrophage colony- ...... different modes of signaling.
@en
prefLabel
Granulocyte-macrophage colony- ...... different modes of signaling.
@en
P2093
P2860
P356
P1476
Granulocyte-macrophage colony- ...... h different modes of signaling
@en
P2093
P2860
P304
P356
10.1074/JBC.271.13.7587
P407
P50
P577
1996-03-01T00:00:00Z