Microsatellite instability, apoptosis, and loss of p53 function in drug-resistant tumor cells.
about
Mechanisms of resistance to alkylating agentsTumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancerMismatch repair deficiency associated with overexpression of the MSH3 geneNoble metals in oncologyStructure and function of the N-terminal 40 kDa fragment of human PMS2: a monomeric GHL ATPase.Flanking Bases Influence the Nature of DNA Distortion by Platinum 1,2-Intrastrand (GG) Cross-LinksDNA methylation changes in epithelial ovarian cancer histotypes.A review of the clinical relevance of mismatch-repair deficiency in ovarian cancerGenomic cloning and characterization of the rat glutathione S-transferase-A3-subunit geneMethylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands.Identification of candidate epigenetic biomarkers for ovarian cancer detection.DNA mismatch repair catalyzed by extracts of mitotic, postmitotic, and senescent Drosophila tissues and involvement of mei-9 gene function for full activity.Mismatch repair processing of carcinogen-DNA adducts triggers apoptosisOverexpression of DDB2 enhances the sensitivity of human ovarian cancer cells to cisplatin by augmenting cellular apoptosis.Apoptosis-related mRNA expression profiles of ovarian cancer cell lines following cisplatin treatment.Selective recognition of a cisplatin-DNA adduct by human mismatch repair proteins.Mutation frequencies at codon 248 of the p53 tumour suppressor gene are not increased in colon cancer cell lines with the RER+ phenotype.The "comparative growth assay": examining the interplay of anti-cancer agents with cells carrying single gene alterations.Mismatch repair protein expression in colorectal cancer.Mismatch repair protein MutL becomes limiting during stationary-phase mutation.Induction of p53-dependent and p53-independent cellular responses by topoisomerase 1 inhibitorsMismatch repair deficiency is associated with resistance to DNA minor groove alkylating agentsA change in microsatellite instability caused by cisplatin-based chemotherapy of ovarian cancerVariation in RNA expression and genomic DNA content acquired during cell culture.p53-Dependent and -independent responses to cisplatin in mouse testicular teratocarcinoma cells.Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct.Chk1/2 inhibition overcomes the cisplatin resistance of head and neck cancer cells secondary to the loss of functional p53.A specific mode of microsatellite instability is a crucial biomarker in adult T-cell leukaemia/lymphoma patients.Prognostic significance of DNA replication errors in young patients with colorectal cancer.Genomic imbalances associated with acquired resistance to platinum analogues.Cisplatin-resistant HeLa cells are resistant to apoptosis via p53-dependent and -independent pathways.Recognition of DNA alterations by the mismatch repair systemThe effect of different chemotherapeutic agents on the enrichment of DNA mismatch repair-deficient tumour cells.Expression of the DNA repair gene MLH1 correlates with survival in patients who have resected pancreatic cancer and have received adjuvant chemoradiation: NRG Oncology RTOG Study 9704.
P2860
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P2860
Microsatellite instability, apoptosis, and loss of p53 function in drug-resistant tumor cells.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Microsatellite instability, ap ...... in drug-resistant tumor cells.
@en
type
label
Microsatellite instability, ap ...... in drug-resistant tumor cells.
@en
prefLabel
Microsatellite instability, ap ...... in drug-resistant tumor cells.
@en
P2093
P1433
P1476
Microsatellite instability, ap ...... in drug-resistant tumor cells
@en
P2093
P304
P407
P577
1996-03-01T00:00:00Z