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Dissecting the p53-Mdm2 feedback loop in vivo: uncoupling the role in p53 stability and activityLow levels of p53 protein and chromatin silencing of p53 target genes repress apoptosis in Drosophila endocycling cells.Limiting the power of p53 through the ubiquitin proteasome pathway.Population distribution and ancestry of the cancer protective MDM2 SNP285 (rs117039649).The Drosophila retinoblastoma binding protein 6 family member has two isoforms and is potentially involved in embryonic patterning.Molecular Evolution of MDM1, a "Duplication-Resistant" Gene in VertebratesNp9, a cellular protein of retroviral ancestry restricted to human, chimpanzee and gorilla, binds and regulates ubiquitin ligase MDM2.MDM2's social network.p53 mRNA and p53 Protein Structures Have Evolved Independently to Interact with MDM2.Loss of tumor suppressor RPL5/RPL11 does not induce cell cycle arrest but impedes proliferation due to reduced ribosome content and translation capacity.Tumor-specific signaling to p53 is mimicked by Mdm2 inactivation in zebrafish: insights from mdm2 and mdm4 mutant zebrafishInhibitors of the p53-Mdm2 interaction increase programmed cell death and produce abnormal phenotypes in the placozoon Trichoplax adhaerens (F.E. Schulze).Correlation between the Expression Level of the MDM Homolog Gene and Inflammatory Lesions in Different Populations of the Model Organism Mytilus Galloprovincialis from Polluted Areas of the Gulf of Naples (Southern Italy)
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Mdm2 in evolution
@en
type
label
Mdm2 in evolution
@en
prefLabel
Mdm2 in evolution
@en
P2860
P356
P1433
P1476
Mdm2 in evolution
@en
P2093
Chandra Verma
P2860
P304
P356
10.1177/1947601912458285
P50
P577
2012-03-01T00:00:00Z