Fatty acid substrate specificities of human prostaglandin-endoperoxide H synthase-1 and -2. Formation of 12-hydroxy-(9Z, 13E/Z, 15Z)- octadecatrienoic acids from alpha-linolenic acid.
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Cyclo-oxygenase-2: pharmacology, physiology, biochemistry and relevance to NSAID therapyProstaglandin E3 metabolism and cancerAdvances in Our Understanding of Oxylipins Derived from Dietary PUFAsMutational and X-ray crystallographic analysis of the interaction of dihomo-gamma -linolenic acid with prostaglandin endoperoxide H synthasesStructure of eicosapentaenoic and linoleic acids in the cyclooxygenase site of prostaglandin endoperoxide H synthase-1Structural Basis of Fatty Acid Substrate Binding to Cyclooxygenase-2Investigating Substrate Promiscuity in Cyclooxygenase-2: THE ROLE OF ARG-120 AND RESIDUES LINING THE HYDROPHOBIC GROOVECyclooxygenase-2-mediated DNA damageTherapies targeting lipid peroxidation in traumatic brain injuryFlexibility of the NSAID binding site in the structure of human cyclooxygenase-2Effects of peroxidation products in thermoxidised dietary oil in female rats during rearing, pregnancy and lactation on their reproductive performance and the antioxidative status of their offspring.Chemically Polymerized Polypyrrole for On-Chip Concentration of Volatile Breath Metabolites.Identification of novel autoxidation products of the omega-3 fatty acid eicosapentaenoic acid in vitro and in vivo.The role of one-electron reduction of lipid hydroperoxides in causing DNA damageLinoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission.The membrane binding domains of prostaglandin endoperoxide H synthases 1 and 2. Peptide mapping and mutational analysis.Spatial requirements for 15-(R)-hydroxy-5Z,8Z,11Z, 13E-eicosatetraenoic acid synthesis within the cyclooxygenase active site of murine COX-2. Why acetylated COX-1 does not synthesize 15-(R)-hete.Different catalytically competent arrangements of arachidonic acid within the cyclooxygenase active site of prostaglandin endoperoxide H synthase-1 lead to the formation of different oxygenated products.In vivo detection of a novel endogenous etheno-DNA adduct derived from arachidonic acid and the effects of antioxidants on its formation.Asthmatics exhibit altered oxylipin profiles compared to healthy individuals after subway air exposure.Proteins modified by the lipid peroxidation aldehyde 9,12-dioxo-10(E)-dodecenoic acid in MCF7 breast cancer cells.Cyclooxygenases: structural and functional insights.The COXes of Danio: from mechanistic model to experimental therapeutics.Cyclooxygenase- and lipoxygenase-mediated DNA damage.ω-3 polyunsaturated fatty acids-derived lipid metabolites on angiogenesis, inflammation and cancerDioscorea japonica extract down-regulates prostaglandin E2 synthetic pathway and induces apoptosis in lung cancer cells.Partnering between monomers of cyclooxygenase-2 homodimersThe chelatable iron pool in living cells: a methodically defined quantity.Non-redundant functions of cyclooxygenases: oxygenation of endocannabinoidsThe structure of ibuprofen bound to cyclooxygenase-2.Evaluation of iron overload.Modulation of adrenocorticotrophin hormone (ACTH)-induced expression of stress-related genes by PUFA in inter-renal cells from European sea bass (Dicentrarchus labrax).Human cyclooxygenase-1 activity and its responses to COX inhibitors are allosterically regulated by nonsubstrate fatty acids.Cholesterol metabolism in the brain: importance of 24S-hydroxylation.Formation of highly reactive cyclopentenone isoprostane compounds (A3/J3-isoprostanes) in vivo from eicosapentaenoic acidThe free fatty acid receptor G protein-coupled receptor 40 (GPR40) protects from bone loss through inhibition of osteoclast differentiation.Crossing the barrier: oxysterols as cholesterol transporters and metabolic modulators in the brain.PUFAs, Bone Mineral Density, and Fragility Fracture: Findings from Human StudiesCovalent adducts arising from the decomposition products of lipid hydroperoxides in the presence of cytochrome c.Toxic oxygenated alpha,beta-unsaturated aldehydes and their study in foods: a review.
P2860
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P2860
Fatty acid substrate specificities of human prostaglandin-endoperoxide H synthase-1 and -2. Formation of 12-hydroxy-(9Z, 13E/Z, 15Z)- octadecatrienoic acids from alpha-linolenic acid.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Fatty acid substrate specifici ...... ids from alpha-linolenic acid.
@en
type
label
Fatty acid substrate specifici ...... ids from alpha-linolenic acid.
@en
prefLabel
Fatty acid substrate specifici ...... ids from alpha-linolenic acid.
@en
P2093
P356
P1476
Fatty acid substrate specifici ...... ids from alpha-linolenic acid.
@en
P2093
Laneuville O
P304
19330-19336
P356
10.1074/JBC.270.33.19330
P407
P577
1995-08-01T00:00:00Z