about
Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEFA crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathwayNucleotide exchange factor ECT2 interacts with the polarity protein complex Par6/Par3/protein kinase Czeta (PKCzeta) and regulates PKCzeta activityA mammalian Rho-specific guanine-nucleotide exchange factor (p164-RhoGEF) without a pleckstrin homology domainRegulation of Sos activity by intramolecular interactions.CDC42 and FGD1 cause distinct signaling and transforming activities.Membrane recruitment of DOCK180 by binding to PtdIns(3,4,5)P3Critical but distinct roles for the pleckstrin homology and cysteine-rich domains as positive modulators of Vav2 signaling and transformationGalpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF.Oligomerization of DH domain is essential for Dbl-induced transformationGGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteinsVav2 activates Rac1, Cdc42, and RhoA downstream from growth factor receptors but not beta1 integrinsMyoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processesEndogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathwayVav2 is required for cell spreadingIdentification of a gene at 11q23 encoding a guanine nucleotide exchange factor: evidence for its fusion with MLL in acute myeloid leukemiaThe DH and PH domains of Trio coordinately engage Rho GTPases for their efficient activationp250GAP, a novel brain-enriched GTPase-activating protein for Rho family GTPases, is involved in the N-methyl-d-aspartate receptor signalingEffector Proteins Exert an Important Influence on the Signaling-active State of the Small GTPase Cdc42Structure of Thermotoga maritima TM0439: implications for the mechanism of bacterial GntR transcription regulators with Zn2+-binding FCD domains.Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?Identification of novel, evolutionarily conserved Cdc42p-interacting proteins and of redundant pathways linking Cdc24p and Cdc42p to actin polarization in yeastYeast protein kinases and the RHO1 exchange factor TUS1 are novel components of the cell integrity pathway in yeast.Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.Functional interaction between the cytoplasmic leucine-zipper domain of HIV-1 gp41 and p115-RhoGEFPlekhg4 is a novel Dbl family guanine nucleotide exchange factor protein for rho family GTPasesCcpg1, a novel scaffold protein that regulates the activity of the Rho guanine nucleotide exchange factor DbsRanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubulesDefective dendrite elongation but normal fertility in mice lacking the Rho-like GTPase activator Dbl.Phosphoinositide 3-kinase C2β regulates RhoA and the actin cytoskeleton through an interaction with DblRegulation of vesicle transport and cell motility by Golgi-localized Dbs.An active form of Vav1 induces migration of mammary epithelial cells by stimulating secretion of an epidermal growth factor receptor ligandNovel regulatory mechanisms for the Dbl family guanine nucleotide exchange factor Cool-2/alpha-Pix.The solution structure and dynamics of the DH-PH module of PDZRhoGEF in isolation and in complex with nucleotide-free RhoA.On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF.Interaction of ezrin with the novel guanine nucleotide exchange factor PLEKHG6 promotes RhoG-dependent apical cytoskeleton rearrangements in epithelial cells.Regulation of the Rac GTPase pathway by the multifunctional Rho GEF Pebble is essential for mesoderm migration in the Drosophila gastrula.Influence of simulated microgravity on the activation of the small GTPase Rho involved in cytoskeletal formation--molecular cloning and sequencing of bovine leukemia-associated guanine nucleotide exchange factorBCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility.
P2860
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P2860
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Dbl family proteins.
@en
type
label
Dbl family proteins.
@en
prefLabel
Dbl family proteins.
@en
P2093
P1476
Dbl family proteins.
@en
P2093
I P Whitehead
K L Rossman
S Campbell
P356
10.1016/S0304-419X(96)00040-6
P577
1997-02-01T00:00:00Z