Biosynthesis and transport of cathepsin D in cultured human fibroblasts.
about
Rabenosyn-5, a novel Rab5 effector, is complexed with hVPS45 and recruited to endosomes through a FYVE finger domainSPE-39 family proteins interact with the HOPS complex and function in lysosomal deliveryDefective endoplasmic reticulum-resident membrane protein CLN6 affects lysosomal degradation of endocytosed arylsulfatase ADemonstration of adenosine deaminase activity in human fibroblast lysosomesTransport of human lysosomal neuraminidase to mature lysosomes requires protective protein/cathepsin A.EBAG9 adds a new layer of control on large dense-core vesicle exocytosis via interaction with SnapinCloning and sequence analysis of cDNA for human cathepsin DIntracellular movement of two mannose 6-phosphate receptors: return to the Golgi apparatusOverexpression of a rat kinase-deficient phosphoinositide 3-kinase, Vps34p, inhibits cathepsin D maturationMolecular characterization of the hypothetical 66.3-kDa protein in mouse: lysosomal targeting, glycosylation, processing and tissue distributionBiochemical characterization and lysosomal localization of the mannose-6-phosphate protein p76 (hypothetical protein LOC196463)Role of AP1 and Gadkin in the traffic of secretory endo-lysosomes.Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimer's disease-linked presenilin 1 A246E mutation can be reversed with cAMPThe role of lysosomal proteinases in MHC class II-mediated antigen processing and presentation.Leishmania donovani resides in modified early endosomes by upregulating Rab5a expression via the downregulation of miR-494.Knock-down of cathepsin D affects the retinal pigment epithelium, impairs swim-bladder ontogenesis and causes premature death in zebrafish.New insights into cathepsin D in mammary tissue development and remodeling.Role for dynamin in late endosome dynamics and trafficking of the cation-independent mannose 6-phosphate receptor.A shortened beta-hexosaminidase alpha-chain in an Italian patient with infantile Tay-Sachs disease.Cathepsin B: association with plasma membrane in metastatic tumors.Pathways involved in targeting and secretion of a lysosomal enzyme in Dictyostelium discoideum.Lysosomal enzyme trafficking in mannose 6-phosphate receptor-positive mouse L-cells: demonstration of a steady state accumulation of phosphorylated acid hydrolasesKinetics of intracellular transport and sorting of lysosomal membrane and plasma membrane proteins.Inhibition of early but not late proteolytic processing events leads to the missorting and oversecretion of precursor forms of lysosomal enzymes in Dictyostelium discoideum.Lysosomes behave as Ca2+-regulated exocytic vesicles in fibroblasts and epithelial cellsRedundant and distinct functions for dynamin-1 and dynamin-2 isoforms.Clathrin light chains function in mannose phosphate receptor trafficking via regulation of actin assembly.Purification, characterization and molecular cloning of human hepatic lysosomal acid lipase.Prolactin promotes the secretion of active cathepsin D at the basal side of rat mammary acini.The tumor-associated antigen EBAG9 negatively regulates the cytolytic capacity of mouse CD8+ T cells.Trans-Golgi reticulum.Two Faces of Cathepsin D: Physiological Guardian Angel and Pathological Demon.Trafficking of lysosomal enzymes in normal and disease states.Yeast as a tool to explore cathepsin D function.A role for crinophagy in pancreatic islet B-cells. Minireview based on a doctoral thesis.Control of lysosomal biogenesis and Notch-dependent tissue patterning by components of the TFEB-V-ATPase axis in Drosophila melanogaster.Proopiomelanocortin-derived peptides are synthesized and released by human keratinocytes.Physiological functions of endosomal proteolysis.Secretion of phosphomannosyl-deficient arylsulphatase A and cathepsin D from isolated human macrophagesLysosomal acid phosphatase is transported to lysosomes via the cell surface.
P2860
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P2860
Biosynthesis and transport of cathepsin D in cultured human fibroblasts.
description
1983 nî lūn-bûn
@nan
1983年の論文
@ja
1983年論文
@yue
1983年論文
@zh-hant
1983年論文
@zh-hk
1983年論文
@zh-mo
1983年論文
@zh-tw
1983年论文
@wuu
1983年论文
@zh
1983年论文
@zh-cn
name
Biosynthesis and transport of cathepsin D in cultured human fibroblasts.
@en
type
label
Biosynthesis and transport of cathepsin D in cultured human fibroblasts.
@en
prefLabel
Biosynthesis and transport of cathepsin D in cultured human fibroblasts.
@en
P2093
P2860
P356
P1476
Biosynthesis and transport of cathepsin D in cultured human fibroblasts.
@en
P2093
Gieselmann V
Pohlmann R
Von Figura K
P2860
P356
10.1083/JCB.97.1.1
P407
P577
1983-07-01T00:00:00Z