Implications of apurinic/apyrimidinic endonuclease in reactive oxygen signaling response after cisplatin treatment of dorsal root ganglion neurons.
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Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1Regulatory role of human AP-endonuclease (APE1/Ref-1) in YB-1-mediated activation of the multidrug resistance gene MDR1.The Response to Oxidative DNA Damage in Neurons: Mechanisms and DiseaseNew perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseasesModeling chemotherapeutic neurotoxicity with human induced pluripotent stem cell-derived neuronal cellsA novel and selective poly (ADP-ribose) polymerase inhibitor ameliorates chemotherapy-induced painful neuropathyCisplatin induces a mitochondrial-ROS response that contributes to cytotoxicity depending on mitochondrial redox status and bioenergetic functionsInhibition of Mitochondrial p53 Accumulation by PFT-μ Prevents Cisplatin-Induced Peripheral Neuropathy.Advanced Oxidative Protein Products Cause Pain Hypersensitivity in Rats by Inducing Dorsal Root Ganglion Neurons Apoptosis via NADPH Oxidase 4/c-Jun N-terminal Kinase Pathways.Redox regulation of DNA repair: implications for human health and cancer therapeutic development.Targeting DNA repair pathways for cancer treatment: what's new?Role of the DNA base excision repair protein, APE1 in cisplatin, oxaliplatin, or carboplatin induced sensory neuropathyIdentification and characterization of human apurinic/apyrimidinic endonuclease-1 inhibitorsFunctional analysis of novel analogues of E3330 that block the redox signaling activity of the multifunctional AP endonuclease/redox signaling enzyme APE1/Ref-1.Dual regulatory roles of human AP-endonuclease (APE1/Ref-1) in CDKN1A/p21 expressionMultimodal assessment of painful peripheral neuropathy induced by chronic oxaliplatin-based chemotherapy in miceThe repair function of the multifunctional DNA repair/redox protein APE1 is neuroprotective after ionizing radiation.Curcumin Ameliorates Functional and Structural Abnormalities in Cisplatin-induced Neuropathy.APE1/Ref-1 role in redox signaling: translational applications of targeting the redox function of the DNA repair/redox protein APE1/Ref-1.Small molecule activation of apurinic/apyrimidinic endonuclease 1 reduces DNA damage induced by cisplatin in cultured sensory neuronsAPE1, the DNA base excision repair protein, regulates the removal of platinum adducts in sensory neuronal cultures by NERS-glutathionylation of cysteine 99 in the APE1 protein impairs abasic endonuclease activity.PAN-811 Blocks Chemotherapy Drug-Induced In Vitro Neurotoxicity, While Not Affecting Suppression of Cancer Cell GrowthCisplatin regulates cell autophagy in endometrial cancer cells via the PI3K/AKT/mTOR signalling pathway.Base excision repair in physiology and pathology of the central nervous systemInhibition of apurinic/apyrimidinic endonuclease I's redox activity revisited.DNA damage response in peripheral nervous system: coping with cancer therapy-induced DNA lesionsBase excision repair in the mammalian brain: implication for age related neurodegenerationMitochondrial DNA damage is associated with reduced mitochondrial bioenergetics in Huntington's disease.Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress: use of APE1 small molecule inhibitors to delineate APE1 functions.The search for treatments to reduce chemotherapy-induced peripheral neuropathy.Oxidative stress and neurodegenerative disordersEmbryonic stem cells lacking the epigenetic regulator Cfp1 are hypersensitive to DNA-damaging agents and exhibit decreased Ape1/Ref-1 protein expression and endonuclease activity.Chemotherapy-induced peripheral neuropathy in adults: a comprehensive update of the literature.Small-molecule inhibitors of DNA damage-repair pathways: an approach to overcome tumor resistance to alkylating anticancer drugs.Mechanisms of distal axonal degeneration in peripheral neuropathies.A review on protein-protein interaction network of APE1/Ref-1 and its associated biological functions.Pharmacotherapeutic options for treating adverse effects of Cisplatin chemotherapy.Identification and Characterization of New Chemical Entities Targeting Apurinic/Apyrimidinic Endonuclease 1 for the Prevention of Chemotherapy-Induced Peripheral NeuropathyEffect of Cytotoxic Compounds on Activity of Antioxidant Enzyme System in MCF-7 and H1299 Cells.
P2860
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P2860
Implications of apurinic/apyrimidinic endonuclease in reactive oxygen signaling response after cisplatin treatment of dorsal root ganglion neurons.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Implications of apurinic/apyri ...... dorsal root ganglion neurons.
@en
type
label
Implications of apurinic/apyri ...... dorsal root ganglion neurons.
@en
prefLabel
Implications of apurinic/apyri ...... dorsal root ganglion neurons.
@en
P2093
P2860
P1433
P1476
Implications of apurinic/apyri ...... dorsal root ganglion neurons.
@en
P2093
Chunlu Guo
Mark R Kelley
Michael R Vasko
Yanlin Jiang
P2860
P304
P356
10.1158/0008-5472.CAN-08-1173
P407
P577
2008-08-01T00:00:00Z