Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5. - Wikidata - awgldk - TriplyDB

Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5.

Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5.

http://www.wikidata.org/entity/Q41485148

about

Phosphodiesterase 10A Is Tethered to a Synaptic Signaling Complex in Striatum A phosphodiesterase 2A isoform localized to mitochondria regulates respiration Phosphodiesterase 2A is a major negative regulator of iNOS expression in lipopolysaccharide-treated mouse alveolar macrophages.Intercellular signaling via cyclic GMP diffusion through gap junctions restarts meiosis in mouse ovarian follicles.Activation of PDE10 and PDE11 phosphodiesterases.Luteinizing Hormone Causes Phosphorylation and Activation of the cGMP Phosphodiesterase PDE5 in Rat Ovarian Follicles, Contributing, Together with PDE1 Activity, to the Resumption of Meiosis Biophysical techniques for detection of cAMP and cGMP in living cells.Inactivation of Non-canonical Cyclic Nucleotides: Hydrolysis and Transport.A Role for Phosphodiesterase 11A (PDE11A) in the Formation of Social Memories and the Stabilization of Mood.Luteinizing hormone signaling phosphorylates and activates the cyclic GMP phosphodiesterase PDE5 in mouse ovarian follicles, contributing an additional component to the hormonally induced decrease in cyclic GMP that reinitiates meiosis.Phosphodiesterase 2: anti-adrenergic friend or hypertrophic foe in heart disease?It takes two transducins to activate the cGMP-phosphodiesterase 6 in retinal rods

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P2860

Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5.

http://www.wikidata.org/entity/Q41485148

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

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2010年論文

@zh-tw

2010年论文

@wuu

2010年论文

@zh

2010年论文

@zh-cn

name

Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5.

@en

type

label

Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5.

@en

prefLabel

Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5.

@en

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J.1476-5381.2010.00977.X

P1433

British Journal of Pharmacology

P1476

Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5

@en

P2093

Doris Koesling

http://www.w3.org/2001/XMLSchema#string

Frank Schwede

http://www.w3.org/2001/XMLSchema#string

Michael Russwurm

http://www.w3.org/2001/XMLSchema#string

Ronald Jäger

http://www.w3.org/2001/XMLSchema#string

P2860

Mechanism for the allosteric regulation of phosphodiesterase 2A deduced from the X-ray structure of a near full-length construct

Binding of cGMP to both allosteric sites of cGMP-binding cGMP-specific phosphodiesterase (PDE5) is required for its phosphorylation

The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use

Molecular determinants for cyclic nucleotide binding to the regulatory domains of phosphodiesterase 2A

cAMP is a ligand for the tandem GAF domain of human phosphodiesterase 10 and cGMP for the tandem GAF domain of phosphodiesterase 11

Inhibition of cyclic GMP-binding cyclic GMP-specific phosphodiesterase (Type 5) by sildenafil and related compounds

Dual acylation of PDE2A splice variant 3: targeting to synaptic membranes

PDE5 is converted to an activated state upon cGMP binding to the GAF A domain

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1645-1660

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scholarly article

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10.1111/J.1476-5381.2010.00977.X

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7

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161

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Hans-Gottfried Genieser

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2010-12-01T00:00:00Z

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45602909

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20698857

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3010573

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