MAL and ternary complex factor use different mechanisms to contact a common surface on the serum response factor DNA-binding domain.
about
Structural and functional analysis of domains mediating interaction between the bagpipe homologue, Nkx3.1 and serum response factorMutations in smooth muscle alpha-actin (ACTA2) cause coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic diseaseDual roles of myocardin-related transcription factors in epithelial mesenchymal transition via slug induction and actin remodelingA competitive transcription factor binding mechanism determines the timing of late cell cycle-dependent gene expression.The essential function for serum response factor in T-cell development reflects its specific coupling to extracellular signal-regulated kinase signalingMyocardin related transcription factors are required for coordinated cell cycle progression.Dual views of SRF: a genomic exposure.MKL1/2 and ELK4 co-regulate distinct serum response factor (SRF) transcription programs in macrophages.Fate-determining mechanisms in epithelial-myofibroblast transition: major inhibitory role for Smad3Activation and repression of cellular immediate early genes by serum response factor cofactors.Shape-induced terminal differentiation of human epidermal stem cells requires p38 and is regulated by histone acetylation.Linking actin dynamics and gene transcription to drive cellular motile functions.RNA export factor Ddx19 is required for nuclear import of the SRF coactivator MKL1Arc in synaptic plasticity: from gene to behavior.Nuclear translocation of myocardin-related transcription factor-A during transforming growth factor beta-induced epithelial to mesenchymal transition of lens epithelial cells.Serum-induced phosphorylation of the serum response factor coactivator MKL1 by the extracellular signal-regulated kinase 1/2 pathway inhibits its nuclear localization.Smooth muscle hyperplasia due to loss of smooth muscle α-actin is driven by activation of focal adhesion kinase, altered p53 localization and increased levels of platelet-derived growth factor receptor-β.Stress-dependent phosphorylation of myocardin-related transcription factor A (MRTF-A) by the p38(MAPK)/MK2 axisMechanical regulation of the proangiogenic factor CCN1/CYR61 gene requires the combined activities of MRTF-A and CREB-binding protein histone acetyltransferase.Inositol polyphosphate multikinase is a coactivator for serum response factor-dependent induction of immediate early genes.Rare, nonsynonymous variant in the smooth muscle-specific isoform of myosin heavy chain, MYH11, R247C, alters force generation in the aorta and phenotype of smooth muscle cells.SAP domain-dependent Mkl1 signaling stimulates proliferation and cell migration by induction of a distinct gene set indicative of poor prognosis in breast cancer patients.Role of serum response factor in the pathogenesis of disease.The myocardin-related transcription factor MKL co-regulates the cellular levels of two profilin isoforms.MRTF potentiates TEAD-YAP transcriptional activity causing metastasis.Envisioning metastasis as a transdifferentiation phenomenon clarifies discordant results on cancer.SRF Co-factors Control the Balance between Cell Proliferation and Contractility.MRTFs- master regulators of EMT.β-catenin and Smad3 regulate the activity and stability of myocardin-related transcription factor during epithelial-myofibroblast transition.Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts.Epithelial Protein Lost in Neoplasm alpha (Eplin-alpha) is transcriptionally regulated by G-actin and MAL/MRTF coactivators.Actin-dependent activation of serum response factor in T cells by the viral oncoprotein tip.A rare human sequence variant reveals myocardin autoinhibition.RPEL motifs link the serum response factor cofactor MAL but not myocardin to Rho signaling via actin bindingRegulation of TGF-β-mediated endothelial-mesenchymal transition by microRNA-27.OTT-MAL is a deregulated activator of serum response factor-dependent gene expressionMKL1 mediates TGF-beta1-induced alpha-smooth muscle actin expression in human renal epithelial cells.Noncanonical hedgehog pathway activation through SRF-MKL1 promotes drug resistance in basal cell carcinomas.Mutual dependence of the MRTF-SRF and YAP-TEAD pathways in cancer-associated fibroblasts is indirect and mediated by cytoskeletal dynamics.Mkl transcription cofactors regulate structural plasticity in hippocampal neurons.
P2860
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P2860
MAL and ternary complex factor use different mechanisms to contact a common surface on the serum response factor DNA-binding domain.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
MAL and ternary complex factor ...... nse factor DNA-binding domain.
@en
type
label
MAL and ternary complex factor ...... nse factor DNA-binding domain.
@en
prefLabel
MAL and ternary complex factor ...... nse factor DNA-binding domain.
@en
P2860
P356
P1476
MAL and ternary complex factor ...... onse factor DNA-binding domain
@en
P2093
Alexia-Ileana Zaromytidou
P2860
P304
P356
10.1128/MCB.01902-05
P407
P577
2006-06-01T00:00:00Z