Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol. - Wikidata - awgldk - TriplyDB

Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol.

Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol.

http://www.wikidata.org/entity/Q41543745

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Molecular pathogenesis and clinical management of Fanconi anemia Hallmarks of progeroid syndromes: lessons from mice and reprogrammed cells Aging of hematopoietic stem cells: DNA damage and mutations?Learning from a paradox: recent insights into Fanconi anaemia through studying mouse models Fanconi anemia and the cell cycle: new perspectives on aneuploidy Balancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?Exonuclease 1 is a critical mediator of survival during DNA double strand break repair in nonquiescent hematopoietic stem and progenitor cells.Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function.Resveratrol increases the bone marrow hematopoietic stem and progenitor cell capacity Improvement of genetic stability in lymphocytes from Fanconi anemia patients through the combined effect of α-lipoic acid and N-acetylcysteine.Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs Oxymetholone therapy of fanconi anemia suppresses osteopontin transcription and induces hematopoietic stem cell cycling.GS-nitroxide (JP4-039)-mediated radioprotection of human Fanconi anemia cell lines.BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair.Disrupted Signaling through the Fanconi Anemia Pathway Leads to Dysfunctional Hematopoietic Stem Cell Biology: Underlying Mechanisms and Potential Therapeutic Strategies.Stem Cell-Specific Mechanisms Ensure Genomic Fidelity within HSCs and upon Aging of HSCs.Fetal origins of hematopoietic failure in a murine model of Fanconi anemia TGF-β Inhibition Rescues Hematopoietic Stem Cell Defects and Bone Marrow Failure in Fanconi Anemia.Endogenous DNA Damage Leads to p53-Independent Deficits in Replicative Fitness in Fetal Murine Fancd2(-/-) Hematopoietic Stem and Progenitor Cells.Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice.Concise Review: Getting to the Core of Inherited Bone Marrow Failures.Oxidative stress-associated protein tyrosine kinases and phosphatases in Fanconi anemia High incidence of female reproductive tract cancers in FA-deficient HPV16-transgenic mice correlates with E7's induction of DNA damage response, an activity mediated by E7's inactivation of pocket proteins.DNA damage response, redox status and hematopoiesis.Resilient and resourceful: genome maintenance strategies in hematopoietic stem cells.Fanconi anemia (FA) and crosslinker sensitivity: Re-appraising the origins of FA definition.Comparison of Different Cytokine Conditions Reveals Resveratrol as a New Molecule for Ex Vivo Cultivation of Cord Blood-Derived Hematopoietic Stem Cells.Recent insights into the molecular basis of Fanconi anemia: genes, modifiers, and drivers.Monoubiquitinated Fanconi anemia D2 (FANCD2-Ub) is required for BCR-ABL1 kinase-induced leukemogenesis.The Sirt1 activator SRT3025 expands hematopoietic stem and progenitor cells and improves hematopoiesis in Fanconi anemia mice.Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function.Evaluation of resveratrol and N-acetylcysteine for cancer chemoprevention in a Fanconi anemia murine model.Fancd2 and p21 function independently in maintaining the size of hematopoietic stem and progenitor cell pool in mice.Current and emerging therapeutic strategies for Fanconi anemia.Metformin improves defective hematopoiesis and delays tumor formation in Fanconi anemia mice.Cell-Cycle-Specific Function of p53 in Fanconi Anemia Hematopoietic Stem and Progenitor Cell Proliferation.Impairment of fetal hematopoietic stem cell function in the absence of Fancd2.Resveratrol counteracts bone loss via mitofilin-mediated osteogenic improvement of mesenchymal stem cells in senescence-accelerated mice.Lnk/Sh2b3 deficiency restores hematopoietic stem cell function and genome integrity in Fancd2 deficient Fanconi anemia

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P2860

Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol.

http://www.wikidata.org/entity/Q41543745

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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2010年论文

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2010年论文

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name

Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol.

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type

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Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol.

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Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol.

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Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol

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Andrew W Duncan

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Devorah C Goldman

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Grover C Bagby

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Laura Eaton

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Laura Marquez-Loza

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Praveen Anur

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R Keaney Rathbun

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William H Fleming

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P2860

SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging

How the fanconi anemia pathway guards the genome

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Hematopoietic fingerprints: an expression database of stem cells and their progeny

Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

Positional cloning of a novel Fanconi anemia gene, FANCD2

Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

Reduced hematopoietic reserves in DNA interstrand crosslink repair-deficient Ercc1-/- mice

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24

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116

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Kevin Watanabe-Smith

Qing-Shuo Zhang

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2010-09-08T00:00:00Z

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46181207

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3012535

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