Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition
about
Metabolite profiling reveals the glutathione biosynthetic pathway as a therapeutic target in triple negative breast cancer.Cystine uptake through the cystine/glutamate antiporter xCT triggers glioblastoma cell death under glucose deprivation.Reverse engineering the cancer metabolic network using flux analysis to understand drivers of human disease.Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.Oncogenic PI3K promotes methionine dependency in breast cancer cells through the cystine-glutamate antiporter xCT.The Central Role of Amino Acids in Cancer Redox Homeostasis: Vulnerability Points of the Cancer Redox Code.Maf1 phenotypes and cell physiology.DNA Damage, Repair, and Cancer Metabolism.Combinatorial CRISPR-Cas9 Metabolic Screens Reveal Critical Redox Control Points Dependent on the KEAP1-NRF2 Regulatory Axis.Aspartate is an endogenous metabolic limitation for tumour growthWe're Not "DON" Yet: Optimal Dosing and Prodrug Delivery ofIbrutinib Resistance Is Reduced by an Inhibitor of Fatty Acid Oxidation in Primary CLL LymphocytesMicroenvironmental regulation of cancer cell metabolism: implications for experimental design and translational studiesA PDX1-ATF transcriptional complex governs β cell survival during stress
P2860
Q42516669-809384F0-611E-46FF-ADC5-7B4C35A32098Q46283642-72F82D5D-8530-4FA3-8E5E-66B2D8195C79Q46614710-71626F86-77A2-4A55-AB9A-6770D6529B18Q47843948-3C6770E8-E5A4-423C-94DD-D5ADECAB9C4DQ48091849-EE37E283-3E34-4ED7-ACAD-BA1E7835227AQ49369970-579DCCE1-2854-4403-B4F9-7742B72088DBQ49720582-FED2C148-277E-48CE-870D-3EEE19A4B198Q49829014-79CBBC46-A64D-40B6-9239-D63D8F860633Q49920405-4842572E-9C60-4CDB-847B-A37E3CB23391Q57095796-49C2C1DA-D4BF-4EBA-AF36-4680D48D59C1Q57165398-1C6F7CF0-F28A-4DEF-94F4-92F49D38CE95Q57491548-DD57E5B5-769A-48EF-B03F-FBACDC59CE7DQ58796751-9250FA80-F079-45D2-926E-73E75A00153EQ58803992-5CDCCF9F-53F6-491E-B993-69F9EF2C8E44
P2860
Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
Environmental cystine drives g ...... ells to glutaminase inhibition
@en
type
label
Environmental cystine drives g ...... ells to glutaminase inhibition
@en
prefLabel
Environmental cystine drives g ...... ells to glutaminase inhibition
@en
P2093
P2860
P356
P1433
P1476
Environmental cystine drives g ...... ells to glutaminase inhibition
@en
P2093
Caroline A Lewis
Chiara Y Waingarten
Laura V Danai
P2860
P356
10.7554/ELIFE.27713
P407
P577
2017-08-15T00:00:00Z