Purification and properties of porcine platelet-derived growth factor.
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cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF moleculesIndependent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathwaysTwo PDGF-B chain residues, arginine 27 and isoleucine 30, mediate receptor binding and activationcDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity to the B-type PDGF receptorStructural characterization of the human platelet-derived growth factor A-chain cDNA and gene: alternative exon usage predicts two different precursor proteinsStructural and functional aspects of platelet-derived growth factorRole of platelet-derived growth factors in physiology and medicineConnective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10.Expression and developmental control of platelet-derived growth factor A-chain and B-chain/Sis genes in rat aortic smooth muscle cells.Cloning and expression of a cDNA coding for the human platelet-derived growth factor receptor: evidence for more than one receptor class.Aberrant expression of receptors for platelet-derived growth factor in an anaplastic thyroid carcinoma cell line.Coexpression of the platelet-derived growth factor (PDGF) B chain and the PDGF beta receptor in isolated pancreatic islet cells stimulates DNA synthesis.Platelet-derived growth factor synthesis in mesangial cells: induction by multiple peptide mitogensCSF-1-induced gene expression in macrophages: dissociation from the mitogenic response.The B chain of PDGF alone is sufficient for mitogenesis.Ca2+-mobilizing actions of platelet-derived growth factor differ from those of bombesin and vasopressin in Swiss 3T3 mouse cells.Sequences of the 5' portion of the human c-sis gene: characterization of the transcriptional promoter and regulation of expression of the protein product by 5' untranslated mRNA sequences.Acetylated lipoproteins impair erythroid growth factor release from endothelial cellsType beta transforming growth factor in human platelets: release during platelet degranulation and action on vascular smooth muscle cells.Induction of platelet-derived growth factor receptor expression in smooth muscle cells and fibroblasts upon tissue culturing.The chemotactic response to PDGF-BB: evidence of a role for Ras.Membrane-anchored form of v-sis/PDGF-B induces mitogenesis without detectable PDGF receptor autophosphorylation.Alternatively spliced platelet-derived growth factor A-chain transcripts are not tumor specific but encode normal cellular proteins.Expression of recombinant platelet-derived growth factor A- and B-chain homodimers in rat-1 cells and human fibroblasts reveals differences in protein processing and autocrine effects.Human melanoma cell lines of primary and metastatic origin express the genes encoding the chains of platelet-derived growth factor (PDGF) and produce a PDGF-like growth factor.Platelet-derived growth factor: mechanism of action and possible in vivo function.B-type receptor for platelet-derived growth factor mediates a chemotactic response by means of ligand-induced activation of the receptor protein-tyrosine kinase.Platelets in pulmonary hypertension: a causative role or a simple association?Differential effects of the various isoforms of platelet-derived growth factor on chemotaxis of fibroblasts, monocytes, and granulocytes.Regulation of expression of the c-sis proto-oncogeneRegulation of platelet-derived growth factor gene expression by transforming growth factor beta and phorbol ester in human leukemia cell lines.PDGF A chain homodimers drive proliferation of bipotential (O-2A) glial progenitor cells in the developing rat optic nerve.Isoform-specific induction of actin reorganization by platelet-derived growth factor suggests that the functionally active receptor is a dimer.Different effects of homo- and heterodimers of platelet-derived growth factor A and B chains on human and mouse fibroblasts.Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types.Highly purified fibroblast-derived growth factor, an SV40-transformed fibroblast-secreted mitogen, is closely related to platelet-derived growth factor.Expression of PDGF A-chain and beta-receptor genes during rat myoblast differentiation.Deletion of the kinase insert sequence of the platelet-derived growth factor beta-receptor affects receptor kinase activity and signal transduction.Purification and analysis of proteinase-resistant mutants of recombinant platelet-derived growth factor-BB exhibiting improved biological activity.Effect of platelet-derived growth factor on voltage-operated calcium channels in rabbit isolated ear artery cells.
P2860
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P2860
Purification and properties of porcine platelet-derived growth factor.
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
1984年论文
@zh
1984年论文
@zh-cn
name
Purification and properties of porcine platelet-derived growth factor.
@en
type
label
Purification and properties of porcine platelet-derived growth factor.
@en
prefLabel
Purification and properties of porcine platelet-derived growth factor.
@en
P2860
P1433
P1476
Purification and properties of porcine platelet-derived growth factor.
@en
P2093
Stroobant P
Waterfield MD
P2860
P304
P407
P577
1984-12-01T00:00:00Z