New insights from spectroscopy into the structure/function relationships of lipoxygenases.
about
Kinetic and spectroscopic studies of N694C lipoxygenase: a probe of the substrate activation mechanism of a nonheme ferric enzymePositional- and stereo-selectivity of fatty acid oxygenation catalysed by mouse (12S)-lipoxygenase isoenzymesDiscovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse librariesPotent and selective inhibitors of human reticulocyte 12/15-lipoxygenase as anti-stroke therapiesDiscovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1.Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase.Mechanistic investigations of human reticulocyte 15- and platelet 12-lipoxygenases with arachidonic acid.Identification of hepatitis C virus inhibitors targeting different aspects of infection using a cell-based assayStructure-activity relationship studies of flavonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2.Substrate activation for O2 reactions by oxidized metal centers in biologyInvestigations of human platelet-type 12-lipoxygenase: role of lipoxygenase products in platelet activation.Substrate specificity changes for human reticulocyte and epithelial 15-lipoxygenases reveal allosteric product regulation.Pseudoperoxidase investigations of hydroperoxides and inhibitors with human lipoxygenasesGeometric structure determination of N694C lipoxygenase: a comparative near-edge X-ray absorption spectroscopy and extended X-ray absorption fine structure studySubstrate specificity effects of lipoxygenase products and inhibitors on soybean lipoxygenase-1.Kinetic and structural investigations of the allosteric site in human epithelial 15-lipoxygenase-2.Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenaseLipidomics of essential fatty acids and oxygenated metabolites.The reactivity of the active metal oxo and hydroxo intermediates and their implications in oxidations.Computational Insights into Five- versus Six-Coordinate Iron Center in Ferrous Soybean Lipoxygenase.Structure/function correlations over binuclear non-heme iron active sitesRole of the Proximal Cysteine Hydrogen Bonding Interaction in Cytochrome P450 2B4 Studied by Cryoreduction, Electron Paramagnetic Resonance, and Electron-Nuclear Double Resonance Spectroscopy.In vitro, fluorescence-quenching and computational studies on the interaction between lipoxygenase and 5-hydroxy-3',4',7-trimethoxyflavone from Lippia nodiflora L.Harnessing Enzymatic Promiscuity in Myxochelin Biosynthesis for the Production of 5-Lipoxygenase Inhibitors.Inflammation, Cancer and Oxidative Lipoxygenase Activity are Intimately Linked.Enzymatic Studies of Isoflavonoids as Selective and Potent Inhibitors of Human Leukocyte 5-Lipo-Oxygenase.The wonderful world of pyridine-2,6-dicarboxamide based scaffolds.13C ENDOR Spectroscopy of Lipoxygenase-Substrate Complexes Reveals the Structural Basis for C-H Activation by Tunneling.Quinoline-based imidazole-fused heterocycles as new inhibitors of 15-lipoxygenase.Oxidation of Naphthalene with a Manganese(IV) Bis(hydroxo) Complex in the Presence of Acid.
P2860
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P2860
New insights from spectroscopy into the structure/function relationships of lipoxygenases.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
New insights from spectroscopy ...... elationships of lipoxygenases.
@en
type
label
New insights from spectroscopy ...... elationships of lipoxygenases.
@en
prefLabel
New insights from spectroscopy ...... elationships of lipoxygenases.
@en
P2093
P1476
New insights from spectroscopy ...... elationships of lipoxygenases.
@en
P2093
P304
P356
10.1016/S1074-5521(97)90113-7
P50
P577
1997-11-01T00:00:00Z